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Found 65 with Last Name = 'fryszman' and Initial = 'o'
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031845((4-Biphenyl-4-yl-1-phosphono-butyl)-phosphonic aci...)
Affinity DataIC50:  0.700nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049232(CHEMBL348349 | Tetrasodium salt of 4-(4'-Methyl-bi...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049227(CHEMBL158707 | Trisodium salt of [1-(Dimethoxy-pho...)
Affinity DataIC50:  5.70nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126193(CHEMBL27660 | {4-[9-(2,2,2-Trifluoro-ethylcarbamoy...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049217(CHEMBL158517 | Tripotassium salt of 1-Phosphono-4-...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126188(CHEMBL28348 | [4-(9-Propylcarbamoyl-9H-fluoren-9-y...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049233(CHEMBL160240 | Tripotassium salt of 4-Biphenyl-4-y...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049230(CHEMBL160267 | Tripotassium salt of 4-{3-[2-(4-Met...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049215(1-Phosphono-4-[3-(2-benzylphenoxy)phenyl]butylsulf...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049228(CHEMBL158448 | Tripotassium salt of 4-{3-[2-(3-Met...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126207((4-{9-[2-(4-Methoxy-phenyl)-ethylcarbamoyl]-9H-flu...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126201(CHEMBL282785 | {4-[9-(2,2,2-Trifluoro-ethylcarbamo...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126201(CHEMBL282785 | {4-[9-(2,2,2-Trifluoro-ethylcarbamo...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126209(CHEMBL283897 | {4-[9-(2,2,2-Trifluoro-ethylcarbamo...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126225(CHEMBL26665 | {4-[9-(2,2,2-Trifluoro-ethylcarbamoy...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126212(CHEMBL280283 | {4-[9-(2,2,2-Trifluoro-ethylcarbamo...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126223(CHEMBL282564 | {4-[9-(2,2,2-Trifluoro-ethylcarbamo...)
Affinity DataIC50:  33nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049224(CHEMBL158862 | Tripotassium salt of 1-Phosphono-4-...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049223(CHEMBL158851 | Tripotassium salt of4-[3-(2-Butyl-p...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126192(CHEMBL265738 | {4-[9-(2,2,2-Trifluoro-ethylcarbamo...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126222(CHEMBL28034 | {4-[9-(2,2,2-Trifluoro-ethylcarbamoy...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126189(CHEMBL27884 | {6-[9-(2,2,2-Trifluoro-ethylcarbamoy...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126198(CHEMBL282516 | {4-[9-(2,2,2-Trifluoro-ethylcarbamo...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126194(CHEMBL280971 | {5-[9-(2,2,2-Trifluoro-ethylcarbamo...)
Affinity DataIC50:  65nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049221(CHEMBL158978 | Tripotassium salt of 4-(4'-But-1-en...)
Affinity DataIC50:  76nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126211(CHEMBL27695 | {4-[9-(2,2,2-Trifluoro-ethylcarbamoy...)
Affinity DataIC50:  85nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126220(CHEMBL431487 | {4-[9-(2,2,2-Trifluoro-ethylcarbamo...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126216(CHEMBL25846 | [4-(9-Propylcarbamoyl-9H-fluoren-9-y...)
Affinity DataIC50:  135nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049225(CHEMBL351866 | Tripotassium salt of 4-(4'-Propyl-b...)
Affinity DataIC50:  144nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126217(CHEMBL26410 | {4-[9-(2,2,2-Trifluoro-ethylcarbamoy...)
Affinity DataIC50:  145nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049236((+/-)-1-Phosphono-4-(3-phenoxyphenyl)butylsulfonic...)
Affinity DataIC50:  169nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049229(1-Phosphono-4-[4-(4-butylphenyl)phenyl]butylsulfon...)
Affinity DataIC50:  192nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049226(CHEMBL158527 | Tripotassium salt of 1-Phosphono-4-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126200(9-[3-(4-Benzoylamino-piperidin-1-yl)-propyl]-9H-fl...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126187(CHEMBL283471 | [4-(9-Benzylcarbamoyl-9H-fluoren-9-...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049220(CHEMBL346762 | Tripotassium salt of 1-Phosphono-4-...)
Affinity DataIC50:  268nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126214(CHEMBL26721 | {4-[9-(2,2,2-Trifluoro-ethylcarbamoy...)
Affinity DataIC50:  280nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049218(CHEMBL159021 | Tripotassium salt of 4-[3-(2-Phenox...)
Affinity DataIC50:  286nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126203(CHEMBL281733 | [4-(9-Butylcarbamoyl-9H-fluoren-9-y...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126206(9-[4-(Dibutoxy-phosphoryl)-butyl]-9H-fluorene-9-ca...)
Affinity DataIC50:  450nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126224((4-{9-[(Pyridin-2-ylmethyl)-carbamoyl]-9H-fluoren-...)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126197(CHEMBL27139 | {4-[9-(2-Morpholin-4-yl-ethylcarbamo...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049238(CHEMBL158154 | trisodium (5E)-6,10-dimethyl-1-phos...)
Affinity DataIC50:  740nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126210(CHEMBL25759 | {4-[9-(4-Amino-benzylcarbamoyl)-9H-f...)
Affinity DataIC50:  890nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049231(CHEMBL347175 | CHEMBL513790 | Trisodium salt of 4-...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049216(CHEMBL160796 | Tripotassium salt of 4-(4'-Ethyl-bi...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126204(2-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-2,3-dih...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126202(9-Allyl-9H-fluorene-9-carboxylic acid ethylamide |...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126205(CHEMBL26466 | [3-(6-Ethoxy-benzothiazol-2-ylsulfan...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50049219(1-Phosphono-4-[4-(4-methylphenyl)phenyl]butylsulfo...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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