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Found 39 with Last Name = 'carabateas' and Initial = 'p'
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039635(2,6-Dichloro-3-(4-methyl-piperazine-1-sulfonyl)-be...)
Affinity DataKi:  0.00700nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039646(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.00800nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50036480(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.00800nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039637(2,6-Dichloro-3-[(2-dimethylamino-ethyl)-methyl-sul...)
Affinity DataKi:  0.0100nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50036478(3-Carboxymethoxy-2,6-dichloro-benzoic acid 4-isopr...)
Affinity DataKi:  0.0110nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50036476(2,6-Dichloro-3-(4-methyl-piperazine-1-sulfonyl)-be...)
Affinity DataKi:  0.0110nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50036477(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.0130nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50036481(2,6-Dichloro-3-[(2-dimethylamino-ethyl)-methyl-sul...)
Affinity DataKi:  0.0130nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50036475(2,6-Dichloro-3-(2-pyrrolidin-1-yl-ethoxy)-benzoic ...)
Affinity DataKi:  0.0140nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039631(2,6-Dichloro-benzoic acid 4-isopropyl-1,1,3-trioxo...)
Affinity DataKi:  0.0300nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039641(2,6-Dichloro-benzoic acid 4-sec-butyl-1,1,3-trioxo...)
Affinity DataKi:  0.0600nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039642(2,6-Dichloro-benzoic acid 4-ethyl-1,1,3-trioxo-1,3...)
Affinity DataKi:  0.170nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50036482(2,6-Dichloro-3-(4-methyl-piperazine-1-sulfonyl)-be...)
Affinity DataKi:  0.200nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039634(2,6-Dichloro-benzoic acid 1,1,3-trioxo-4-phenyl-1,...)
Affinity DataKi:  1nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039644(2,6-Dichloro-benzoic acid 4-methyl-1,1,3-trioxo-1,...)
Affinity DataKi:  2nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039636(2,6-Dichloro-benzoic acid 1,1,3-trioxo-1,3-dihydro...)
Affinity DataKi:  2.70nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039640(2,6-Dimethyl-benzoic acid 1,1,3-trioxo-1,3-dihydro...)
Affinity DataKi:  4nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039638(2,6-Dimethoxy-benzoic acid 1,1,3-trioxo-1,3-dihydr...)
Affinity DataKi:  8nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039639(2,6-Difluoro-benzoic acid 1,1,3-trioxo-1,3-dihydro...)
Affinity DataKi:  8nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039632(2,6-Dibromo-benzoic acid 1,1,3-trioxo-1,3-dihydro-...)
Affinity DataKi:  8.5nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50036479(1,1-Dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulfanylmeth...)
Affinity DataKi:  15nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039633(2-Acetylamino-6-chloro-benzoic acid 1,1,3-trioxo-1...)
Affinity DataKi:  18nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039647(2,6-Dichloro-benzoic acid 4-tert-butyl-1,1,3-triox...)
Affinity DataKi:  26nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039643(Benzoic acid 1,1,3-trioxo-1,3-dihydro-1lambda*6*-b...)
Affinity DataKi:  31nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039645(2,6-Bis-trifluoromethyl-benzoic acid 1,1,3-trioxo-...)
Affinity DataKi:  37nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50039648(Acetic acid 1,1,3-trioxo-1,3-dihydro-1lambda*6*-be...)
Affinity DataKi:  102nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407402(CHEMBL2093896)
Affinity DataIC50:  2.10E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407403(CHEMBL2092889)
Affinity DataIC50:  2.90E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407402(CHEMBL2093896)
Affinity DataIC50: >3.00E+4nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407402(CHEMBL2093896)
Affinity DataIC50: >3.00E+4nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407403(CHEMBL2092889)
Affinity DataIC50: >3.00E+4nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407404(CHEMBL2092890)
Affinity DataIC50:  3.80E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50369030(CHEMBL1788206)
Affinity DataIC50:  3.80E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50031720((Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-p...)
Affinity DataIC50:  4.40E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50369029(CHEMBL1788304)
Affinity DataIC50:  8.50E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50369029(CHEMBL1788304)
Affinity DataIC50: >1.00E+5nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407404(CHEMBL2092890)
Affinity DataIC50: >1.00E+5nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50369030(CHEMBL1788206)
Affinity DataIC50:  1.26E+5nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50031720((Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-p...)
Affinity DataIC50: >3.00E+5nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed