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Found 11 with Last Name = 'chène' and Initial = 'p'
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177710((3-acetylamino-5-oxo-5,11-dihydro-10-thia-dibenzo[...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50295258(CHEMBL571444 | N2-(benzo[d]thiazol-6-yl)-N6-tert-b...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of ATPase activity of human topoisomerase 2 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177713(2-(5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohep...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177711((5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177711((5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of ATPase activity of Tyr473Ala mutated Helicase4 in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177712((2-methyl-5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]c...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50295259(CHEMBL549357 | N2-(benzo[d]thiazol-6-yl)-N6-cycloh...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of ATPase activity of human topoisomerase 2 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50382115(CHEMBL2024321)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of p53 derived peptide binding to MDM4 using fluorescent dye Cy5 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50382117(CHEMBL2024323)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of p53 derived peptide binding to MDM4 using fluorescent dye Cy5 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50382116(CHEMBL2024322)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of p53 derived peptide binding to MDM4 using fluorescent dye Cy5 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50382114(CHEMBL2024320)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of p53 derived peptide binding to MDM4 using fluorescent dye Cy5 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed