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Found 55 with Last Name = 'dunkel' and Initial = 'p'
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50403106(CHEMBL2216916)
Affinity DataKi:  18nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429811(CHEMBL2337670)
Affinity DataKi:  78nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50403105(CHEMBL2216917)
Affinity DataKi:  178nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429807(CHEMBL2337674)
Affinity DataKi:  266nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429813(CHEMBL2337676)
Affinity DataKi:  436nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429812(CHEMBL2337669)
Affinity DataKi:  637nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2222 as susbtrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429812(CHEMBL2337669)
Affinity DataKi:  675nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429808(CHEMBL2337673)
Affinity DataKi:  1.27E+3nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2222 as susbtrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429813(CHEMBL2337676)
Affinity DataKi:  1.51E+3nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2222 as susbtrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429814(CHEMBL2337675)
Affinity DataKi:  1.65E+3nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429809(CHEMBL2337672)
Affinity DataKi:  1.67E+3nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429809(CHEMBL2337672)
Affinity DataKi:  1.96E+3nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2222 as susbtrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429814(CHEMBL2337675)
Affinity DataKi:  2.15E+3nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2222 as susbtrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429808(CHEMBL2337673)
Affinity DataKi:  2.69E+3nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429811(CHEMBL2337670)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2222 as susbtrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429807(CHEMBL2337674)
Affinity DataKi:  5.08E+3nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2222 as susbtrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429810(CHEMBL2337671)
Affinity DataKi:  5.18E+3nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429810(CHEMBL2337671)
Affinity DataKi:  5.19E+3nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2222 as susbtrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429809(CHEMBL2337672)
Affinity DataIC50:  665nMAssay Description:Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429810(CHEMBL2337671)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102391(US8536210, 40)
Affinity DataIC50:  3.50E+3nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102357(US8536210, 6)
Affinity DataIC50:  4.30E+3nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102360(US8536210, 9)
Affinity DataIC50:  1.49E+4nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429808(CHEMBL2337673)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102369(US8536210, 18)
Affinity DataIC50:  1.80E+4nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50365128(CHEMBL1949835 | CHEMBL2216906)
Affinity DataIC50:  2.25E+4nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 insect cells assessed as inhibition of poly(Glu,Tyr) 4:1 substrate phosphorylation by radiome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102370(US8536210, 19)
Affinity DataIC50:  2.90E+4nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102368(US8536210, 17)
Affinity DataIC50:  3.00E+4nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102358(US8536210, 7)
Affinity DataIC50:  4.00E+4nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102378(US8536210, 27)
Affinity DataIC50:  4.10E+4nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429807(CHEMBL2337674)
Affinity DataIC50:  4.26E+4nMAssay Description:Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102373(US8536210, 22)
Affinity DataIC50:  4.80E+4nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102367(US8536210, 16)
Affinity DataIC50:  5.30E+4nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102372(US8536210, 21)
Affinity DataIC50:  5.80E+4nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50349611(CHEMBL1808951 | CHEMBL2216905)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 insect cells assessed as inhibition of poly(Glu,Tyr) 4:1 substrate phosphorylation by radiome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102359(US8536210, 8)
Affinity DataIC50:  9.50E+4nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102352(US8536210, 1)
Affinity DataIC50:  1.02E+5nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102375(US8536210, 24)
Affinity DataIC50:  1.06E+5nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102374(US8536210, 23)
Affinity DataIC50:  1.11E+5nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102376(US8536210, 25)
Affinity DataIC50:  1.13E+5nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Semmelweis Egyetem

US Patent
LigandPNGBDBM102363(US8536210, 12)
Affinity DataIC50:  1.80E+5nMpH: 7.2 T: 2°CAssay Description:For determining the SSAO/VAP-1 activity, the colorimetric method described by Holt, A (Holt, A., Biochem. 244, 384, 1997) for monoamine oxidase and a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429814(CHEMBL2337675)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429813(CHEMBL2337676)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429812(CHEMBL2337669)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429811(CHEMBL2337670)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429814(CHEMBL2337675)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human alphavbeta3 integrin receptor after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429813(CHEMBL2337676)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human alphavbeta3 integrin receptor after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429812(CHEMBL2337669)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human alphavbeta3 integrin receptor after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429811(CHEMBL2337670)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human alphavbeta3 integrin receptor after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429810(CHEMBL2337671)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human alphavbeta3 integrin receptor after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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