TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 369nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 377nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 385nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 462nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 543nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.64E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 2.19E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 2.21E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 2.62E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of mouse SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.150nMAssay Description:Antagonist activity at human SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity at mouse SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Antagonist activity at mouse SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Antagonist activity at mouse SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Displacement of [125I]SS-14 from mouse SSTR3 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Displacement of [125I]SS-14 from mouse SSTR3 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibition of mouse SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Inhibition of mouse SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Antagonist activity at human SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.530nMAssay Description:Displacement of [125I]-NDP-R-MSH from human MC4R expressed in CHO cells after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Antagonist activity at mouse SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.660nMAssay Description:Binding affinity to human somatostatin receptor type 3More data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.660nMAssay Description:Displacement of [125I]SS-28 from human SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]SS-14 from mouse SSTR3 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: 0.710nMAssay Description:Displacement of [125I]-NDP-R-MSH from human MC4R expressed in CHO cells after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.730nMAssay Description:Antagonist activity at mouse SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.740nMAssay Description:Displacement of [125I]SS-28 from human SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.760nMAssay Description:Displacement of [125I]SS-28 from human SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.780nMAssay Description:Inhibition of human SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.780nMAssay Description:Antagonist activity at human SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.780nMAssay Description:Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.830nMAssay Description:Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Displacement of [125I]-NDP-R-MSH from human MC4R expressed in CHO cells after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Displacement of [125I]-NDP-R-MSH from human MC4R expressed in CHO cells after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human melanocortin 4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.940nMAssay Description:Displacement of [125I]SS-28 from human SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair