Affinity DataKi: 0.160nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of human cathepsin K by gelatin zymographic analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
TargetThioredoxin reductase(Mycobacterium tuberculosis)
Msd Animal Health Innovation
Curated by ChEMBL
Msd Animal Health Innovation
Curated by ChEMBL
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TrxR after 10 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
TargetThioredoxin reductase(Mycobacterium tuberculosis)
Msd Animal Health Innovation
Curated by ChEMBL
Msd Animal Health Innovation
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TrxR after 10 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetThioredoxin reductase(Mycobacterium tuberculosis)
Msd Animal Health Innovation
Curated by ChEMBL
Msd Animal Health Innovation
Curated by ChEMBL
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TrxR after 10 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetThioredoxin reductase(Mycobacterium tuberculosis)
Msd Animal Health Innovation
Curated by ChEMBL
Msd Animal Health Innovation
Curated by ChEMBL
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TrxR after 10 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
TargetThioredoxin reductase(Mycobacterium tuberculosis)
Msd Animal Health Innovation
Curated by ChEMBL
Msd Animal Health Innovation
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TrxR after 10 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...More data for this Ligand-Target Pair