Affinity DataIC50: 0.0100nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Berlex Laboratories
Curated by ChEMBL
Berlex Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0660nMAssay Description:Inhibitory activity as antagonist of AII on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Berlex Laboratories
Curated by ChEMBL
Berlex Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibitory activity as antagonist of AII on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Berlex Laboratories
Curated by ChEMBL
Berlex Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibitory activity as antagonist of AII on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Berlex Laboratories
Curated by ChEMBL
Berlex Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibitory activity as antagonist of AII on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Berlex Laboratories
Curated by ChEMBL
Berlex Laboratories
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:The compound was tested for its ability to displace [3H]Angiotensin II (300 ng/mL) from rabbit adrenal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair