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Found 324 with Last Name = 'bao' and Initial = 'r'
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604879(N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-...)
Affinity DataIC50:  0.400nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604880(N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-...)
Affinity DataIC50:  0.600nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597750((S)—N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-...)
Affinity DataIC50:  0.720nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597779((S)—N-(5-Cyano-4-((2-methoxyethyl)amino)pyrid...)
Affinity DataIC50:  0.740nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597781((R)—N-(5-Cyano-4-((2-methoxyethyl)amino)pyrid...)
Affinity DataIC50:  0.740nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604845(N-(5-Cyano-4-(((trans)-2-methoxycyclopentyl)amino)...)
Affinity DataIC50:  0.800nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597749((R)—N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-...)
Affinity DataIC50:  0.900nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM50509955(CHEMBL4518346 | US11608332, Example 45)
Affinity DataIC50:  0.920nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM50509954(CHEMBL4446965 | US11608332, Example 46)
Affinity DataIC50:  0.920nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM50509949(CHEMBL4475216 | US11667631, Example 29)
Affinity DataIC50:  0.960nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604926(N-(5-Cyano-4-(((trans)-4-methoxytetrahydrofuran-3-...)
Affinity DataIC50:  0.970nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597813(N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-...)
Affinity DataIC50:  0.980nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM50509963(CHEMBL4439119 | US11667631, Example 60)
Affinity DataIC50:  0.990nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM523870(5-(4-Cyclopropyl-1H-imidazol-1-yl)-N-(6-(5,5-dimet...)
Affinity DataIC50:  1nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597802(N-(5-Cyano-4-(((R)-1-methoxypropan-2-yl)amino)pyri...)
Affinity DataIC50:  1nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597798(N-(5-Cyano-4-(((S)-tetrahydrofuran-3-yl)amino)pyri...)
Affinity DataIC50:  1.01nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597799(N-(5-Cyano-4-(((R)-tetrahydrofuran-3-yl)amino)pyri...)
Affinity DataIC50:  1.01nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604921(N-(5-Cyano-4-trans-((1,2)-2-methoxycyclobutoxy)pyr...)
Affinity DataIC50:  1.02nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597818(N-(5-Cyano-4-(((trans)-4-methoxytetrahydrofuran-3-...)
Affinity DataIC50:  1.07nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM50509971(CHEMBL4457168 | US11608332, Example 87)
Affinity DataIC50:  1.10nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604897(N-(5-Cyano-4-(((trans)-4-methoxytetrahydrofuran-3-...)
Affinity DataIC50:  1.12nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597805(Preparation of N-(5-cyano-4-(((R)-1-methoxypropan-...)
Affinity DataIC50:  1.16nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597794(N-(5-Cyano-4-(((R)-1-methoxypropan-2-yl)oxy)pyridi...)
Affinity DataIC50:  1.20nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM50509969(CHEMBL4562284 | US11667631, Example 34)
Affinity DataIC50:  1.27nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604909((R)-N-(5-Cyano-4-(3-methoxypyrrolidin-1-yl)pyridin...)
Affinity DataIC50:  1.28nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597797((S)-N-(5-Cyano-4-(oxetan-3-ylamino)pyridin-2-yl)-7...)
Affinity DataIC50:  1.32nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604912((R)-N-(5-Cyano-4-(3-methoxypyrrolidin-1-yl)pyridin...)
Affinity DataIC50:  1.33nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604930(N-(5-Cyano-4-(((3,4)-trans-4-methoxytetrahydro-2H-...)
Affinity DataIC50:  1.34nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597800(N-(5-Cyano-4-((trans)-4-methoxytetrahydrofuran-3-y...)
Affinity DataIC50:  1.34nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM523874((R)-5-(4-(tert-Butyl)-1H-imidazol-1-yl)-2-fluoro-4...)
Affinity DataIC50:  1.40nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM50509962(CHEMBL4532389 | US11667631, Example 33)
Affinity DataIC50:  1.44nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597778(N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-...)
Affinity DataIC50:  1.45nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597812((R)—N-(5-Cyano-4-((2-methoxyethyl)amino)pyrid...)
Affinity DataIC50:  1.47nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597817((R)—N-(5-Cyano-4-(3-methoxypyrrolidin-1-yl)py...)
Affinity DataIC50:  1.49nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597811(N-(5-Cyano-4-(((trans)-4-methoxytetrahydrofuran-3-...)
Affinity DataIC50:  1.52nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597780((R)—N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-...)
Affinity DataIC50:  1.62nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604924((R)-N-(5-Cyano-4-(3-methoxypyrrolidin-1-yl)pyridin...)
Affinity DataIC50:  1.62nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604925(N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-...)
Affinity DataIC50:  1.62nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597808(N-(5-Cyano-4-(((S)-tetrahydrofuran-3-yl)amino)pyri...)
Affinity DataIC50:  1.67nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604887(N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-...)
Affinity DataIC50:  1.71nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597810(N-(5-Cyano-4-(((R)-tetrahydrofuran-3-yl)amino)pyri...)
Affinity DataIC50:  1.75nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604883(N-(5-Cyano-4-((1-(methoxymethyl))cyclopropyl)amino...)
Affinity DataIC50:  1.77nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM523868((R)-5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-...)
Affinity DataIC50:  1.80nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597782((R)-6-((1-Acetyl-N-methylpyrrolidin-2-carboxamido)...)
Affinity DataIC50:  1.88nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM523896(5-(4-Cyclopropyl-1H-imidazol-1-yl)-N-(6-(6′,...)
Affinity DataIC50:  1.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM523886((S)-5-(4-Cyclopropyl-1H-imidazol-1-yl)-N-(6-(5-eth...)
Affinity DataIC50:  1.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM523892((R)-5-(4-Cyclopropyl-1H-imidazol-1-yl)-N-(6-(5-eth...)
Affinity DataIC50:  1.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM523884((S)-5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-...)
Affinity DataIC50:  1.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597786(N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-...)
Affinity DataIC50:  1.94nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597814((S)—N-(5-Cyano-4-((tetrahydrofuran-3-yl)amino...)
Affinity DataIC50:  1.95nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
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