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Found 133 with Last Name = 'fridman' and Initial = 'r'
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82122(Vinylsulfone, 7)
Affinity DataKi:  0.530nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  64nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  320nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82121(Gama, gama-dimethyl derivative, 6)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82119(Sulfoxide, 4)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82120(Alpha, alpha-dimethyl derivative, 5)
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-25(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human MMP25 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50346797(CHEMBL1795351)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50346802(CHEMBL1795861)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-25(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human MMP25 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50346799(CHEMBL1795858)
Affinity DataIC50:  4nMAssay Description:Inhibition of human MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50346800(CHEMBL1795859)
Affinity DataIC50:  6nMAssay Description:Inhibition of human MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of human MMP8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50:  11nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50203527((6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,...)
Affinity DataIC50:  14nMAssay Description:Inhibition of porcine spleen ADAM17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50346801(CHEMBL1795860)
Affinity DataIC50:  17nMAssay Description:Inhibition of human MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346802(CHEMBL1795861)
Affinity DataIC50:  21nMAssay Description:Inhibition of human MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50203527((6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50:  30nMAssay Description:Inhibition of human MMP8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-25(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346797(CHEMBL1795351)
Affinity DataIC50:  34nMAssay Description:Inhibition of human MMP25 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-25(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50:  38nMAssay Description:Inhibition of human MMP25 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346802(CHEMBL1795861)
Affinity DataIC50:  38nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346797(CHEMBL1795351)
Affinity DataIC50:  46nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346799(CHEMBL1795858)
Affinity DataIC50:  50nMAssay Description:Inhibition of human MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human MMP1 by fluorometric assayMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50:  63nMAssay Description:Inhibition of human MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-25(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346800(CHEMBL1795859)
Affinity DataIC50:  76nMAssay Description:Inhibition of human MMP25 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346800(CHEMBL1795859)
Affinity DataIC50:  77nMAssay Description:Inhibition of human MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346797(CHEMBL1795351)
Affinity DataIC50:  79nMAssay Description:Inhibition of human MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346799(CHEMBL1795858)
Affinity DataIC50:  84nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346800(CHEMBL1795859)
Affinity DataIC50:  93nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50:  112nMAssay Description:Inhibition of human MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-25(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346802(CHEMBL1795861)
Affinity DataIC50:  170nMAssay Description:Inhibition of human MMP25 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50:  180nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346797(CHEMBL1795351)
Affinity DataIC50:  200nMAssay Description:Inhibition of human MMP8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-25(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346801(CHEMBL1795860)
Affinity DataIC50:  220nMAssay Description:Inhibition of human MMP25 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346800(CHEMBL1795859)
Affinity DataIC50:  280nMAssay Description:Inhibition of human MMP8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346801(CHEMBL1795860)
Affinity DataIC50:  320nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-25(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346799(CHEMBL1795858)
Affinity DataIC50:  340nMAssay Description:Inhibition of human MMP25 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346799(CHEMBL1795858)
Affinity DataIC50:  440nMAssay Description:Inhibition of human MMP8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50:  490nMAssay Description:Inhibition of human MMP8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346802(CHEMBL1795861)
Affinity DataIC50:  500nMAssay Description:Inhibition of human MMP8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346801(CHEMBL1795860)
Affinity DataIC50:  650nMAssay Description:Inhibition of human MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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