Affinity DataKi: 0.0160nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,L591M](Human immunodeficiency virus type 1)
Georgia State University
Georgia State University
Affinity DataKi: 0.0300nMAssay Description:The inhibition assays were performed in microtiter plate wells by mixing enzyme and fluorescent peptide substrate in the presence of inhibitor compou...More data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0955nMAssay Description:Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Georgia State University
Georgia State University
Affinity DataKi: 0.220nM ΔG°: -57.3kJ/molepH: 5.6 T: 2°CAssay Description:The inhibition assays were performed in microtiter plate wells by mixing enzyme and fluorescent peptide substrate in the presence of inhibitor compou...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.275nMAssay Description:Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-...More data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.302nMAssay Description:Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-...More data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-...More data for this Ligand-Target Pair
Affinity DataKi: 0.331nMAssay Description:Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-...More data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.355nMAssay Description:Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-...More data for this Ligand-Target Pair
Affinity DataKi: 0.355nMAssay Description:Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-...More data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of matrix metalloproteinase-3(MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]LSD form human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair