Affinity DataKi: 0.135nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.135nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M4 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M4 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.178nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M2 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.178nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M2 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 ADR expressed in HEK293T cell membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M5 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M5 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.302nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.309nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.324nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.324nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.331nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.372nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.525nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.562nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.589nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.603nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.661nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 0.661nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 0.676nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.692nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.692nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 0.776nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]NMS from human M3 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 0.813nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.851nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.891nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 0.891nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.891nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.912nMAssay Description:Displacement of [3H]NMS from human M1 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 0.933nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.955nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.977nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]NMS from human M1 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]NMS from human M3 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universita Di Firenze
Curated by ChEMBL
Universita Di Firenze
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]prazosin from recombinant human alpha-1d adrenergic receptor expressed in CHO cell membranes after 30 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I]-p-iodoclonidin from I1-imidazoline receptor in rat PC12 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair