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Found 178 with Last Name = 'naik' and Initial = 'r'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50073254(Anthranilamide derivative | CHEMBL408110)
Affinity DataKi:  0.0600nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285701(Anthranilamide derivative | CHEMBL313767)
Affinity DataKi:  0.0700nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285698(Anthranilamide derivative | CHEMBL315500)
Affinity DataKi:  0.260nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285700(Anthranilamide derivative | CHEMBL315742)
Affinity DataKi:  0.450nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285703(Anthranilamide derivative | CHEMBL315928)
Affinity DataKi:  1.20nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285696(Anthranilamide derivative | CHEMBL85640)
Affinity DataKi:  1.20nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285691(Anthranilamide derivative | CHEMBL264622)
Affinity DataKi:  2.40nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285695(Anthranilamide derivative | CHEMBL86263)
Affinity DataKi:  3nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285699(Anthranilamide derivative | CHEMBL87879)
Affinity DataKi:  12nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285690(Anthranilamide derivative | CHEMBL87309)
Affinity DataKi:  20nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285702(Anthranilamide derivative | CHEMBL314408)
Affinity DataKi:  20nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285692(1N-[1-benzyl-2,3-dihydroxy-4-(2-methylcarboxamidop...)
Affinity DataKi:  41nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285693(Anthranilamide derivative | CHEMBL84884)
Affinity DataKi:  91nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMalate dehydrogenase, cytoplasmic(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50250242(CHEMBL4068781)
Affinity DataKi:  740nMAssay Description:Competitive inhibition of human MDH1 expressed in Escherichia coli using oxaloacetic acid as substrate in presence of NADH after 30 mins by double re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50250242(CHEMBL4068781)
Affinity DataKi:  950nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50400094(CHEMBL427092)
Affinity DataKi:  1.90E+3nMAssay Description:Competitive inhibition of MDH2 (unknown origin) using varying NADH level by oxaloacetate-dependent NADH oxidation based Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50031520(CHEMBL3359147)
Affinity DataKi:  4.30E+3nMAssay Description:Competitive inhibition of MDH2 (unknown origin) using varying NADH level by oxaloacetate-dependent NADH oxidation based Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285694(Anthranilamide derivative | CHEMBL314004)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285697(Anthranilamide derivative | CHEMBL313254)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548675(CHEMBL4800042)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548673(CHEMBL4748390)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50084621(BMN 673 | Talazoparib)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548679(CHEMBL4747106)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548674(CHEMBL4787850)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50179011(CHEMBL380456 | Moracin P)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated trans-2-octenoyl N-acetylcysteamine (t-o-NAC thioester) substrate reduction assessed as decrease in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548676(CHEMBL4786854)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548681(CHEMBL4753410)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548683(CHEMBL4789581)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548672(CHEMBL4781887)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548684(CHEMBL4746309)
Affinity DataIC50:  1nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50084621(BMN 673 | Talazoparib)
Affinity DataIC50:  1nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548677(CHEMBL4755076)
Affinity DataIC50:  1nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548685(CHEMBL4776820)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548677(CHEMBL4755076)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548679(CHEMBL4747106)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548680(CHEMBL4741921)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548681(CHEMBL4753410)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548673(CHEMBL4748390)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548675(CHEMBL4800042)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548678(CHEMBL4777158)
Affinity DataIC50:  5nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548682(CHEMBL4776507)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548674(CHEMBL4787850)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548685(CHEMBL4776820)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50548672(CHEMBL4781887)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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