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Found 131 with Last Name = 'parsons' and Initial = 'rb'
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM13016(1,2,3,4-tetrahydroisoquinoline | CHEMBL14346 | THI...)
Affinity DataKi:  4.70E+7nM ΔG°:  -7.88kJ/molepH: 8.6 T: 2°CAssay Description:Enzyme activity assays were performed as previously described with NNMT (16.25 ug/mL, 550 nM) in 50 mM Tris buffer (pH 8.6) containing 1 mM DTT (all ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM60920(thionicotinamide)
Affinity DataKi:  6.60E+7nM ΔG°:  -7.01kJ/molepH: 8.6 T: 2°CAssay Description:Enzyme activity assays were performed as previously described with NNMT (16.25 ug/mL, 550 nM) in 50 mM Tris buffer (pH 8.6) containing 1 mM DTT (all ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM60924(quinoline 3-carboxamide)
Affinity DataKi:  9.70E+7nM ΔG°:  -6.02kJ/molepH: 8.6 T: 2°CAssay Description:Enzyme activity assays were performed as previously described with NNMT (16.25 ug/mL, 550 nM) in 50 mM Tris buffer (pH 8.6) containing 1 mM DTT (all ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50047015(CHEMBL14474 | Chinolin | benzo[b]pyridine | quinol...)
Affinity DataKi:  1.02E+8nM ΔG°:  -5.89kJ/molepH: 8.6 T: 2°CAssay Description:Enzyme activity assays were performed as previously described with NNMT (16.25 ug/mL, 550 nM) in 50 mM Tris buffer (pH 8.6) containing 1 mM DTT (all ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM60921(isoquinoline)
Affinity DataKi:  2.02E+8nM ΔG°:  -4.12kJ/molepH: 8.6 T: 2°CAssay Description:Enzyme activity assays were performed as previously described with NNMT (16.25 ug/mL, 550 nM) in 50 mM Tris buffer (pH 8.6) containing 1 mM DTT (all ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588067(CHEMBL5189197)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588085(CHEMBL5173204)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50506000(CHEMBL4445337)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588063(CHEMBL5172454)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588087(CHEMBL5182376)
Affinity DataIC50:  54nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588082(CHEMBL5196219)
Affinity DataIC50:  61nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588089(CHEMBL5175456)
Affinity DataIC50:  69nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50506011(CHEMBL4436698)
Affinity DataIC50:  83nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588076(CHEMBL5183289)
Affinity DataIC50:  190nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588079(CHEMBL5198886)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588095(CHEMBL5171598)
Affinity DataIC50:  360nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588081(CHEMBL5209274)
Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445716(CHEMBL3104317)
Affinity DataIC50:  530nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588049(CHEMBL5196381)
Affinity DataIC50:  570nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588078(CHEMBL5205644)
Affinity DataIC50:  640nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445693(CHEMBL3104448)
Affinity DataIC50:  800nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588062(CHEMBL5203440)
Affinity DataIC50:  860nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588099(CHEMBL5191939)
Affinity DataIC50:  960nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCholinesterase(Equus caballus (Horse))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445693(CHEMBL3104448)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of equine serum butyrylcholinesterase using S-butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588068(CHEMBL5189085)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588077(CHEMBL5184681)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588088(CHEMBL5204937)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588080(CHEMBL5194159)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445719(CHEMBL3104452)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588054(CHEMBL5184031)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445715(CHEMBL3104318)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445716(CHEMBL3104317)
Affinity DataIC50:  1.71E+3nMAssay Description:Inhibition of equine serum butyrylcholinesterase using S-butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445719(CHEMBL3104452)
Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of equine serum butyrylcholinesterase using S-butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588096(CHEMBL5191670)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445718(CHEMBL3104453)
Affinity DataIC50:  2.05E+3nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445715(CHEMBL3104318)
Affinity DataIC50:  2.18E+3nMAssay Description:Inhibition of equine serum butyrylcholinesterase using S-butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445721(CHEMBL3104450)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445718(CHEMBL3104453)
Affinity DataIC50:  2.68E+3nMAssay Description:Inhibition of equine serum butyrylcholinesterase using S-butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588086(CHEMBL5190850)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588050(CHEMBL5183652)
Affinity DataIC50:  2.84E+3nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCholinesterase(Equus caballus (Horse))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445694(CHEMBL3104447)
Affinity DataIC50:  2.91E+3nMAssay Description:Inhibition of equine serum butyrylcholinesterase using S-butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588075(CHEMBL5180479)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCholinesterase(Equus caballus (Horse))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445695(CHEMBL3104446)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of equine serum butyrylcholinesterase using S-butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM197173(Sinefungin)
Affinity DataIC50:  3.90E+3nMpH: 8.6 T: 2°CAssay Description:Enzyme activity assays were performed as previously described with NNMT (16.25 ug/mL, 550 nM) in 50 mM Tris buffer (pH 8.6) containing 1 mM DTT (all ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445714(CHEMBL3104319)
Affinity DataIC50:  3.95E+3nMAssay Description:Inhibition of equine serum butyrylcholinesterase using S-butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Utrecht University

LigandPNGBDBM50588072(CHEMBL5180115)
Affinity DataIC50:  4.03E+3nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445714(CHEMBL3104319)
Affinity DataIC50:  4.04E+3nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445717(CHEMBL3104454)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of equine serum butyrylcholinesterase using S-butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50445717(CHEMBL3104454)
Affinity DataIC50:  4.23E+3nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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