Compile Data Set for Download or QSAR
maximum 50k data
Found 78 with Last Name = 'reynolds' and Initial = 'rc'
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50396023(CHEMBL2169919)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-SAM in recombinant human His-tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21-Gold (DE3) cells incubated for ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50396023(CHEMBL2169919)
Affinity DataIC50:  0.860nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Lactobacillus casei DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  71nMAssay Description:Inhibition of recombinant human DNMT1 using poly(dl-dC) as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium avium)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  190nMAssay Description:Inhibition of Mycobacterium avium DHFRMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Russian Academy of Science

Curated by ChEMBL
LigandPNGBDBM50241779(CHEMBL4082159)
Affinity DataIC50:  216nMAssay Description:Inhibition of Mycobacterium tuberculosis LeuRS expressed in Escherichia coli Rosetta (DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  620nMAssay Description:Inhibition of Lactobacillus casei DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  760nMAssay Description:Inhibition of recombinant human PRMT3 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551137(CHEMBL4765125)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of recombinant human G9a using histone H3 (1 to 21) as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551132(CHEMBL4777038)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Pneumocystis carinii DHFRMore data for this Ligand-Target Pair
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359406(CHEMBL1926717)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359412(CHEMBL1926724)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551136(CHEMBL4757320)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359407(CHEMBL1926719)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551135(CHEMBL4740900)
Affinity DataIC50:  2.24E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of recombinant human EZH2 using core histone as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551134(CHEMBL4761584)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551136(CHEMBL4757320)
Affinity DataIC50:  2.53E+4nMAssay Description:Inhibition of recombinant human PRMT3 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359400(CHEMBL1929425)
Affinity DataIC50:  2.68E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359410(CHEMBL1926722)
Affinity DataIC50:  2.73E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359413(CHEMBL1926725)
Affinity DataIC50:  2.95E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551120(CHEMBL1889068)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359411(CHEMBL1926723)
Affinity DataIC50:  3.41E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359398(CHEMBL110168)
Affinity DataIC50:  3.42E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359401(CHEMBL1929426)
Affinity DataIC50:  3.43E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359408(CHEMBL1926720)
Affinity DataIC50:  3.48E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551130(CHEMBL4757791)
Affinity DataIC50:  3.69E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359399(CHEMBL106808)
Affinity DataIC50:  3.81E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551128(CHEMBL1700259)
Affinity DataIC50:  4.08E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359402(CHEMBL1929427)
Affinity DataIC50:  4.57E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359414(CHEMBL1926726)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359415(CHEMBL1926727)
Affinity DataIC50:  4.62E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359405(CHEMBL457349)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551136(CHEMBL4757320)
Affinity DataIC50:  5.36E+4nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359409(CHEMBL1926721)
Affinity DataIC50:  5.46E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551121(CHEMBL1701619)
Affinity DataIC50:  5.49E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551142(CHEMBL4755929)
Affinity DataIC50:  5.56E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551122(CHEMBL3183870)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551136(CHEMBL4757320)
Affinity DataIC50:  6.14E+4nMAssay Description:Inhibition of recombinant human G9a using histone H3 (1 to 21) as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551136(CHEMBL4757320)
Affinity DataIC50:  6.15E+4nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551131(CHEMBL4787257)
Affinity DataIC50:  6.92E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551131(CHEMBL4787257)
Affinity DataIC50:  6.94E+4nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551136(CHEMBL4757320)
Affinity DataIC50:  7.98E+4nMAssay Description:Inhibition of recombinant human SET7/9 using core histone as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551128(CHEMBL1700259)
Affinity DataIC50:  8.29E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 78 total ) | Next | Last >>
Jump to: