TargetEpidermal growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim Rcv
Curated by ChEMBL
Boehringer Ingelheim Rcv
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of SOS1-mediated proliferation of human DLD-1 cells assessed as proliferation incubated for 5 to 14 days by AlamarBlue based 3D proliferat...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of BRD4 in human MV411 cells assessed as reduction in MYC mRNA expressionMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim Rcv
Curated by ChEMBL
Boehringer Ingelheim Rcv
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SOS1-mediated proliferation of human NCI-H520 cells assessed as proliferation incubated for 5 to 14 days by AlamarBlue based 3D prolife...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim Rcv
Curated by ChEMBL
Boehringer Ingelheim Rcv
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim Rcv
Curated by ChEMBL
Boehringer Ingelheim Rcv
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...More data for this Ligand-Target Pair
Affinity DataKd: 104nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 123nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 350nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 751nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.49E+3nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 469nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.93E+4nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 937nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 301nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair