Affinity DataKi: 0.400nM ΔG°: -53.3kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 4.80nM ΔG°: -47.2kJ/mole EC50: 1.80nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -46.6kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 9.10nM ΔG°: -45.6kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 9.20nM ΔG°: -45.6kJ/mole EC50: 61.9nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -45.1kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -45.1kJ/mole EC50: 646nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 14nM ΔG°: -44.5kJ/mole EC50: 1.25nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 14nM ΔG°: -44.5kJ/mole EC50: 104nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 16nM ΔG°: -44.2kJ/mole EC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 18nM ΔG°: -43.9kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 19nM ΔG°: -43.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 20nM ΔG°: -43.6kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 21nM ΔG°: -43.5kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 22nM ΔG°: -43.4kJ/mole EC50: 3.13nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 170nM ΔG°: -38.4kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
Affinity DataKi: 200nM ΔG°: -38.0kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University of Mississippi
Curated by ChEMBL
University of Mississippi
Curated by ChEMBL
Affinity DataIC50: 521nMAssay Description:Inhibition of LFA1/ICAM1-mediated CFSE-labeled TPA-stimulated human HL60 cell adhesion to ICAM1 expressing human HeLa cells after 45 mins by fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysisMore data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University of Mississippi
Curated by ChEMBL
University of Mississippi
Curated by ChEMBL
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >2.14E+4nMAssay Description:Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysisMore data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University of Mississippi
Curated by ChEMBL
University of Mississippi
Curated by ChEMBL
Affinity DataIC50: >4.30E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated CFSE-labeled TPA-stimulated human HL60 cell adhesion to ICAM1 expressing human HeLa cells after 45 mins by fluoresc...More data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University of Mississippi
Curated by ChEMBL
University of Mississippi
Curated by ChEMBL
Affinity DataIC50: >4.44E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cellsMore data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University of Mississippi
Curated by ChEMBL
University of Mississippi
Curated by ChEMBL
Affinity DataIC50: >5.20E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cellsMore data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University of Mississippi
Curated by ChEMBL
University of Mississippi
Curated by ChEMBL
Affinity DataIC50: >5.22E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.04E+5nMAssay Description:Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysisMore data for this Ligand-Target Pair