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Found 1392 with Last Name = 'christian' and Initial = 's'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470573(US10815215, Example 233 | US11130745, Example 233 ...)
Affinity DataIC50:  0nMAssay Description:The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller et al., 19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629242((−)-N-{4-[5-fluoro-6-methyl-3-(pyridin-2-yl)...)
Affinity DataIC50:  0.739nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629261(N-{4-[5-chloro-3-(pyridin-2-yl)-1H-pyrrolo[3,2-b]p...)
Affinity DataIC50:  0.941nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629245((+)-2-(4-fluorophenyl)-N-{4-[3-(pyridin-2-yl)-1H-p...)
Affinity DataIC50:  0.949nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470358(4-(3-ethyl-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-tri...)
Affinity DataIC50:  1nMAssay Description:Assay 2: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470561(1-(4-[(2-chloro-6-fluorophenyl)carbamoyl]-2-fluoro...)
Affinity DataIC50:  1nMAssay Description:Assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470561(1-(4-[(2-chloro-6-fluorophenyl)carbamoyl]-2-fluoro...)
Affinity DataIC50:  1nMAssay Description:DHODH enzymatic assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470358(4-(3-ethyl-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-tri...)
Affinity DataIC50:  1nMAssay Description:The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller et al. 196...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470561(1-(4-[(2-chloro-6-fluorophenyl)carbamoyl]-2-fluoro...)
Affinity DataIC50:  1nMAssay Description:The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller et al., 19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470358(4-(3-ethyl-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-tri...)
Affinity DataIC50:  1nMAssay Description:The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller et al., 19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM490402(5-fluoro-N-(2-methylphenyl)-4-(3-oxo-5,6,7,8-tetra...)
Affinity DataIC50:  1nMAssay Description:Assay—2: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629241((+)-2-(4-fluorophenyl)-N-{4-[5-fluoro-3-(pyridin-2...)
Affinity DataIC50:  1nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM490338(N-(2-chloro-6-fluorophenyl)-5-fluoro-4-(3-oxo-5,6,...)
Affinity DataIC50:  1nMAssay Description:Assay—1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM490556(5-fluoro-N-(2-methylphenyl)-4-(3-oxo-5,6,7,8-tetra...)
Affinity DataIC50:  1nMAssay Description:Assay—2: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629257(2-(4-fluorophenyl)-N-{4-[7-(pyridin-2-yl)-5H-pyrro...)
Affinity DataIC50:  1.02nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629252(2-(4-fluorophenyl)-N-[4-(3-phenyl-1H-pyrrolo[3,2-b...)
Affinity DataIC50:  1.04nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629243(2-(4-fluorophenyl)-N-{4-[3-(pyridin-2-yl)-1H-pyrro...)
Affinity DataIC50:  1.06nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM490548(5-fluoro-4-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3...)
Affinity DataIC50:  1.20nMAssay Description:Assay—2: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629280(US20230339939, Example 42)
Affinity DataIC50:  1.23nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629258(2-(4-fluorophenyl)-N-[4-(7-phenyl-5H-pyrrolo[3,2-c...)
Affinity DataIC50:  1.30nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629288(N-{4-[5-fluoro-3-(5-fluoropyridin-2-yl)-1H-pyrrolo...)
Affinity DataIC50:  1.42nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470552(1-(4-[(2-chloro-6-fluorophenyl)carbamoyl]-2-fluoro...)
Affinity DataIC50:  1.5nMAssay Description:DHODH enzymatic assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470555(1-(4-[(2,6-dichlorophenyl)carbamoyl]-2-fluoro-5-{[...)
Affinity DataIC50:  1.5nMAssay Description:Assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470552(1-(4-[(2-chloro-6-fluorophenyl)carbamoyl]-2-fluoro...)
Affinity DataIC50:  1.5nMAssay Description:Assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM490357(5-fluoro-N-[2-(methylamino)phenyl]-4-(3-oxo-5,6,7,...)
Affinity DataIC50:  1.5nMAssay Description:Assay—2: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470555(1-(4-[(2,6-dichlorophenyl)carbamoyl]-2-fluoro-5-{[...)
Affinity DataIC50:  1.5nMAssay Description:The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller et al., 19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470552(1-(4-[(2-chloro-6-fluorophenyl)carbamoyl]-2-fluoro...)
Affinity DataIC50:  1.5nMAssay Description:The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller et al., 19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470555(1-(4-[(2,6-dichlorophenyl)carbamoyl]-2-fluoro-5-{[...)
Affinity DataIC50:  1.5nMAssay Description:DHODH enzymatic assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629260(N-{4-[7-chloro-3-(pyridin-2-yl)-1H-pyrrolo[3,2-b]p...)
Affinity DataIC50:  1.60nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629265(N-{4-[5-fluoro-6-methyl-3-(pyridin-2-yl)-1H-pyrrol...)
Affinity DataIC50:  1.60nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629259(2-(4-fluorophenyl)-N-{4-[7-(pyridin-2-yl)-5H-pyrro...)
Affinity DataIC50:  1.66nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629251((+)-2-(4-fluorophenyl)-N-[4-(3-phenyl-1H-pyrrolo[3...)
Affinity DataIC50:  1.66nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629239(2-(4-fluorophenyl)-N-{4-[5-fluoro-3-(pyridin-2-yl)...)
Affinity DataIC50:  1.66nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629247(2-(4-fluorophenyl)-N-{4-[6-fluoro-3-(pyridin-2-yl)...)
Affinity DataIC50:  1.68nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629268(US20230339939, Example 30)
Affinity DataIC50:  1.69nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629286((+)-N-{4-[5-fluoro-3-(5-fluoropyridin-2-yl)-1H-pyr...)
Affinity DataIC50:  1.69nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM490359(N-(4-amino-2-methylphenyl)-5-fluoro-4-(3-oxo-5,6,7...)
Affinity DataIC50:  1.70nMAssay Description:Assay—1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629244(2-(4-fluorophenyl)-N-{4-[3-(pyridin-2-yl)-1H-pyrro...)
Affinity DataIC50:  1.73nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM490359(N-(4-amino-2-methylphenyl)-5-fluoro-4-(3-oxo-5,6,7...)
Affinity DataIC50:  1.80nMAssay Description:Assay—2: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470513(4-(3-ethyl-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-tri...)
Affinity DataIC50:  1.80nMAssay Description:The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller et al., 19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470513(4-(3-ethyl-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-tri...)
Affinity DataIC50:  1.80nMAssay Description:The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller et al. 196...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470513(4-(3-ethyl-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-tri...)
Affinity DataIC50:  1.80nMAssay Description:Assay 2: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629253(2-(4-fluorophenyl)-N-{4-[3-(3-fluorophenyl)-1H-pyr...)
Affinity DataIC50:  1.87nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629255(N-{4-[3-(5-chlorothiophen-2-yl)-1H-pyrrolo[3,2-b]p...)
Affinity DataIC50:  1.88nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470565(1-(4-[(2-chloro-6-fluorophenyl)carbamoyl]-2-fluoro...)
Affinity DataIC50:  2nMAssay Description:Assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470565(1-(4-[(2-chloro-6-fluorophenyl)carbamoyl]-2-fluoro...)
Affinity DataIC50:  2nMAssay Description:The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller et al., 19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM470565(1-(4-[(2-chloro-6-fluorophenyl)carbamoyl]-2-fluoro...)
Affinity DataIC50:  2nMAssay Description:DHODH enzymatic assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM490360(5-fluoro-N-(2-fluoro-6-methylphenyl)-4-(3-oxo-5,6,...)
Affinity DataIC50:  2nMAssay Description:Assay—2: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM490393(N-(2-chloro-6-methylphenyl)-5-fluoro-4-(3-oxo-5,6,...)
Affinity DataIC50:  2nMAssay Description:Assay—1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bayer Aktiengellschaft

US Patent
LigandPNGBDBM490333(N-(2,6-difluorophenyl)-5-fluoro-4-(3-oxo-5,6,7,8-t...)
Affinity DataIC50:  2nMAssay Description:Assay—2: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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