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Found 62 with Last Name = 'corvaisier' and Initial = 's'
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079375(CHEMBL3417008 | US9663465, 20)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079377(CHEMBL3417007)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079367(CHEMBL3416998)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM28583(5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in BHK cell membrane measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079365(CHEMBL3416996 | US9663465, 8)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079366(CHEMBL3416997 | US9663465, 12)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50562651(CHEMBL4788250)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membrane measured after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079369(CHEMBL3417000 | US9663465, 11)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membrane measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079368(CHEMBL3416999 | US9663465, 16)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079364(CHEMBL3416995 | US9663465, 7)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM84950(CAS_183782 | NSC_183782 | RS 67333)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50562651(CHEMBL4788250)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membrane measured after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079370(CHEMBL3417001)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079363(CHEMBL3414597 | US9663465, 6)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079371(CHEMBL3417002)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079372(CHEMBL3417003)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079376(CHEMBL3417005)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079374(CHEMBL3417006)
Affinity DataKi:  122nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079373(CHEMBL3417004)
Affinity DataKi:  193nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate peincubated for 5 mins followed by substrate addition by DTNB-reagen...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079370(CHEMBL3417001)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataIC50:  16nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079373(CHEMBL3417004)
Affinity DataIC50:  24nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human BuChE using S-butyrylthiocholine as substrate preincubated for 30 mins followed by substrate addition and measured after 25 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079371(CHEMBL3417002)
Affinity DataIC50:  45nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079366(CHEMBL3416997 | US9663465, 12)
Affinity DataIC50:  57nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079365(CHEMBL3416996 | US9663465, 8)
Affinity DataIC50:  69nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate peincubated for 5 mins followed by substrate addition by DTNB-reagent based El...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079367(CHEMBL3416998)
Affinity DataIC50:  118nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079372(CHEMBL3417003)
Affinity DataIC50:  121nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079368(CHEMBL3416999 | US9663465, 16)
Affinity DataIC50:  222nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079369(CHEMBL3417000 | US9663465, 11)
Affinity DataIC50:  321nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM84950(CAS_183782 | NSC_183782 | RS 67333)
Affinity DataIC50:  403nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079364(CHEMBL3416995 | US9663465, 7)
Affinity DataIC50:  577nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50562650(CHEMBL4744490)
Affinity DataIC50:  835nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate peincubated for 5 mins followed by substrate addition by DTNB-reagent based El...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50562650(CHEMBL4744490)
Affinity DataIC50:  927nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate peincubated for 5 mins followed by substrate addition by DTNB-reagent based El...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079363(CHEMBL3414597 | US9663465, 6)
Affinity DataIC50:  937nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS-7 cells assessed as inhibition of 5HT-induced cAMP accumulation preincubated for 7 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079374(CHEMBL3417006)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079370(CHEMBL3417001)
Affinity DataIC50:  1.84E+3nMAssay Description:Inhibition of equine serum BuChE pre-incubated for 5 mins before butyrylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50562651(CHEMBL4788250)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS-7 cells assessed as inhibition of 5HT-induced cAMP accumulation preincubated for 7 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079375(CHEMBL3417008 | US9663465, 20)
Affinity DataIC50:  2.72E+3nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of equine serum BuChE pre-incubated for 5 mins before butyrylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079374(CHEMBL3417006)
Affinity DataIC50:  3.64E+3nMAssay Description:Inhibition of equine serum BuChE pre-incubated for 5 mins before butyrylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079366(CHEMBL3416997 | US9663465, 12)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of equine serum BuChE pre-incubated for 5 mins before butyrylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079375(CHEMBL3417008 | US9663465, 20)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of equine serum BuChE pre-incubated for 5 mins before butyrylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  4.15E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition and measured after 25 mins by D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

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