TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...More data for this Ligand-Target Pair
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...More data for this Ligand-Target Pair
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...More data for this Ligand-Target Pair
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Mus musculus)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...More data for this Ligand-Target Pair
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Mus musculus)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...More data for this Ligand-Target Pair
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...More data for this Ligand-Target Pair
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Mus musculus)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...More data for this Ligand-Target Pair
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...More data for this Ligand-Target Pair
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of MGAT2 in human intestinal microsomes using 2-oleyl-sn-glycerol and [14C]-oleyl-coenzyme A as substrate after 10 to 15 mins by liquid sc...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair