Affinity DataKi: 3.00E+4nMAssay Description:Inhibition of full length recombinant mouse N-terminal GST-tagged PAD2 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethyl ester...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 4.70E+4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PAD4 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethylester ...More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+4nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 6.40E+4nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 7.10E+4nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 8.80E+4nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 1.12E+5nMAssay Description:Inhibition of full length human GST-tagged PAD1 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 1.55E+5nMAssay Description:Inhibition of full length human GST-tagged PAD1 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 1.79E+5nMAssay Description:Inhibition of full length recombinant mouse N-terminal GST-tagged PAD2 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethyl ester...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 1.80E+5nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 1.83E+5nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PAD4 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethylester ...More data for this Ligand-Target Pair
Affinity DataKi: 2.82E+5nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 3.53E+5nMAssay Description:Inhibition of full length human GST-tagged PAD1 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 3.84E+5nMAssay Description:Inhibition of human PAD1 using BAEE as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.45E+5nMAssay Description:Inhibition of human PAD1 using BAEE as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 4.88E+5nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 5.54E+5nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 5.91E+5nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 6.02E+5nMAssay Description:Inhibition of human PAD1 using BAEE as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 6.32E+5nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PAD4 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethylester ...More data for this Ligand-Target Pair
Affinity DataKi: 7.14E+5nMAssay Description:Inhibition of full length recombinant mouse N-terminal GST-tagged PAD2 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethyl ester...More data for this Ligand-Target Pair
Affinity DataKi: 9.64E+5nMAssay Description:Inhibition of full length human GST-tagged PAD1 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+6nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 1.09E+6nMAssay Description:Inhibition of full length human GST-tagged PAD1 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 1.43E+6nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PAD4 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethylester ...More data for this Ligand-Target Pair
Affinity DataKi: 1.84E+6nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 2.42E+6nMAssay Description:Inhibition of human PAD1 using BAEE as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 2.82E+6nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 4.62E+6nMAssay Description:Inhibition of full length recombinant mouse N-terminal GST-tagged PAD2 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethyl ester...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 4.64E+6nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PAD4 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethylester ...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length human GST-tagged PAD1 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length human GST-tagged PAD1 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length human GST-tagged PAD1 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair