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Found 20 with Last Name = 'milicevic sephton' and Initial = 's'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute Of Technology (Eth) Zurich

Curated by ChEMBL
LigandPNGBDBM50395548(CHEMBL2164783)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute Of Technology (Eth) Zurich

Curated by ChEMBL
LigandPNGBDBM50395546(CHEMBL2164785)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute Of Technology (Eth) Zurich

Curated by ChEMBL
LigandPNGBDBM50395547(CHEMBL2164784)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute Of Technology (Eth) Zurich

Curated by ChEMBL
LigandPNGBDBM50395545(CHEMBL2164787)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute Of Technology (Eth) Zurich

Curated by ChEMBL
LigandPNGBDBM50395544(CHEMBL2164788)
Affinity DataKi:  31.2nMAssay Description:Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)
Affinity DataIC50:  1nMAssay Description:Inhibition of HIV1 Reverse transcriptase polymerase assessed as decrease in digoxigenin and biotin-dUTP incorporation into DNA using poly(A)/oligo(dT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity using biotin-labeled double-stranded HIV1 LTR U5 donor DNA substrate pretreated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Moloney murine leukemia virus)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Murine leukemia virus reverse transcriptase RNase H using 18-nucleotide 3'-fluorescein-labeled RNA/5'-dabcyl-labeled DNA hybrid as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H using 18-nucleotide 3'-fluorescein-labeled RNA/5'-dabcyl-labeled DNA hybrid as substrate measured af...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)
Affinity DataIC50:  2.81E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H using 18-nucleotide 3'-fluorescein-labeled RNA/5'-dabcyl-labeled DNA hybrid as substrate measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50512545(CHEMBL4535359)
Affinity DataIC50:  4.68E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H using 18-nucleotide 3'-fluorescein-labeled RNA/5'-dabcyl-labeled DNA hybrid as substrate measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Moloney murine leukemia virus)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50512545(CHEMBL4535359)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Murine leukemia virus reverse transcriptase RNase H using 18-nucleotide 3'-fluorescein-labeled RNA/5'-dabcyl-labeled DNA hybrid as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50512544(CHEMBL4465677)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 Reverse transcriptase polymerase assessed as decrease in digoxigenin and biotin-dUTP incorporation into DNA using poly(A)/oligo(dT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50512545(CHEMBL4535359)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 Reverse transcriptase polymerase assessed as decrease in digoxigenin and biotin-dUTP incorporation into DNA using poly(A)/oligo(dT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50512544(CHEMBL4465677)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity using biotin-labeled double-stranded HIV1 LTR U5 donor DNA substrate pretreated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Moloney murine leukemia virus)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50512544(CHEMBL4465677)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Murine leukemia virus reverse transcriptase RNase H using 18-nucleotide 3'-fluorescein-labeled RNA/5'-dabcyl-labeled DNA hybrid as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50512544(CHEMBL4465677)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H using 18-nucleotide 3'-fluorescein-labeled RNA/5'-dabcyl-labeled DNA hybrid as substrate measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50512545(CHEMBL4535359)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity using biotin-labeled double-stranded HIV1 LTR U5 donor DNA substrate pretreated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50512545(CHEMBL4535359)
Affinity DataKd:  3.80E+4nMAssay Description:Binding affinity to recombinant wild-type full length HIV1 reverse transcriptase p66/p51 expressed in Escherichia coli by biolayer interferometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute Of Technology (Eth) Zurich

Curated by ChEMBL
LigandPNGBDBM50395544(CHEMBL2164788)
Affinity DataKd:  70nMAssay Description:Binding affinity to mGluR5 receptor in Sprague-Dawley rat brain by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed