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Found 95 with Last Name = 'ratnofsky' and Initial = 's'
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: <1nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092232(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: <1nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: <1nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092228(4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50: <1nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: <1nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092228(4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50:  2nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: <2nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  2nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  5nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM8798(CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  5nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092232(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: <8nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092231((4-Phenoxy-phenyl)-quinazolin-4-yl-amine | CHEMBL3...)
Affinity DataIC50: <8nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  10nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  11nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8798(CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  14nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092228(4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50:  16nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50145570(1H-Indole-2-carboxylic acid (4-{4-amino-1-[4-(4-me...)
Affinity DataIC50:  20nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  23nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM8807(CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...)
Affinity DataIC50:  24nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM8803(CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)
Affinity DataIC50:  28nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50145571(1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...)
Affinity DataIC50:  37nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50092232(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  40nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  48nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145570(1H-Indole-2-carboxylic acid (4-{4-amino-1-[4-(4-me...)
Affinity DataIC50:  56nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8807(CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...)
Affinity DataIC50:  57nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  58nMAssay Description:Inhibition of tie-2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50145572(3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-...)
Affinity DataIC50:  64nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145571(1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50092228(4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50:  70nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  75nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  84nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  85nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  88nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM8797(CHEMBL297363 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)
Affinity DataIC50:  93nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145572(3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-...)
Affinity DataIC50:  97nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50092229(7-tert-Butyl-5-(4-chloro-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  150nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  150nMAssay Description:Inhibition of tie-2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  151nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8803(CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)
Affinity DataIC50:  155nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  170nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8797(CHEMBL297363 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)
Affinity DataIC50:  189nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092229(7-tert-Butyl-5-(4-chloro-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  220nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  250nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  270nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  317nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092230(7-Cyclopentyl-5-(2-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50:  390nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  430nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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