Compile Data Set for Download or QSAR
maximum 50k data
Found 74 with Last Name = 'sunami' and Initial = 's'
LigandPNGBDBM50109937((R)-2-[(Indane-2-carbonyl)-amino]-3-naphthalen-1-y...)
Affinity DataIC50:  7.30nMAssay Description:Tested for the inhibition of Candida GGTase I in Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109938(9H-Xanthene-9-carboxylic acid {(R)-2-(3,4-dichloro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Candida geranylgeranyl transferase I at 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109933(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50:  17nMAssay Description:Tested for the inhibition of Candida GGTase I in Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109933(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50:  17nMAssay Description:Tested for the inhibition of Candida GGTase I in Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109940(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50:  31nMAssay Description:Tested for the inhibition of Candida GGTase I in Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109935(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50:  240nMAssay Description:Inhibition of Candida geranylgeranyl transferase I at 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109934(CHEMBL347650 | Indan-2-carboxylic acid {(R)-1-[2-(...)
Affinity DataIC50:  350nMAssay Description:Inhibition of Candida geranylgeranyl transferase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109936(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50:  780nMAssay Description:Tested for the inhibition of Candida GGTase I in Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109939(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Candida geranylgeranyl transferase I at 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109933(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human geranylgeranyl transferase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249689(2,10-Dihydroxy-6-({[6-(hydroxymethyl)pyridin-2-yl]...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249696(2,10-Dihydroxy-6-({[3-(hydroxymethyl)pyridin-4-yl]...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249674(2,10-Dihydroxy-6-[(pyridin-4-ylmethyl)amino]-13-(b...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249679(CHEMBL447069 | edotecarin)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50109933(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249690(2,10-Dihydroxy-6-({[5-(hydroxymethyl)pyridin-2-yl]...)
Affinity DataEC50:  120nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249695(2,10-Dihydroxy-6-({[6-(hydroxymethyl)pyridin-3-yl]...)
Affinity DataEC50:  130nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249696(2,10-Dihydroxy-6-({[3-(hydroxymethyl)pyridin-4-yl]...)
Affinity DataEC50:  130nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249691(2,10-Dihydroxy-6-({[4-(hydroxymethyl)pyridin-2-yl]...)
Affinity DataEC50:  160nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249669(6-[(2-Furylmethyl)amino]-2,10-dihydroxy-13-(beta-D...)
Affinity DataEC50:  180nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249675(2,10-Dihydroxy-6-[(pyrazin-2-ylmethyl)amino]-13-(b...)
Affinity DataEC50:  210nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249687(2,10-Dihydroxy-6-{[3-(hydroxymethyl)benzyl]amino}-...)
Affinity DataEC50:  220nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249683(2,10-Dihydroxy-6-[(4-cyanobenzyl)amino]-13-(beta-D...)
Affinity DataEC50:  300nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249692(2,10-Dihydroxy-6-({[3-(hydroxymethyl)pyridin-2-yl]...)
Affinity DataEC50:  400nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249674(2,10-Dihydroxy-6-[(pyridin-4-ylmethyl)amino]-13-(b...)
Affinity DataEC50:  420nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249670(6-[(3-Furylmethyl)amino]-2,10-dihydroxy-13-(beta-D...)
Affinity DataEC50:  470nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249685(2,10-Dihydroxy-6-{[4-(hydroxymethyl)benzyl]amino}-...)
Affinity DataEC50:  600nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249680(2,10-Dihydroxy-6-[(4-methylbenzyl)amino]-13-(beta-...)
Affinity DataEC50:  800nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249672(2,10-Dihydroxy-6-[(pyridin-2-ylmethyl)amino]-13-(b...)
Affinity DataEC50:  800nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249683(2,10-Dihydroxy-6-[(4-cyanobenzyl)amino]-13-(beta-D...)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249676(2,10-Dihydroxy-6-[(quinolin-2-ylmethyl)amino]-13-(...)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249681(2,10-Dihydroxy-6-[(4-nitrolbenzyl)amino]-13-(beta-...)
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249671(2,10-Dihydroxy-6-[(1H-pyrrol-2-ylmethyl)amino]-13-...)
Affinity DataEC50:  6.50E+3nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249678(2,10-Dihydroxy-6-[(quinolin-4-ylmethyl)amino]-13-(...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249682(2,10-Dihydroxy-6-[(4-bromobenzyl)amino]-13-(beta-D...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249693(2,10-Dihydroxy-6-({[4-(hydroxymethyl)pyridin-3-yl]...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249673(2,10-Dihydroxy-6-[(pyridin-3-ylmethyl)amino]-13-(b...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249677(2,10-Dihydroxy-6-[(quinolin-3-ylmethyl)amino]-13-(...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249680(2,10-Dihydroxy-6-[(4-methylbenzyl)amino]-13-(beta-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249697(2,10-Dihydroxy-6-({[2-(hydroxymethyl)pyridin-4-yl]...)
Affinity DataEC50:  100nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249674(2,10-Dihydroxy-6-[(pyridin-4-ylmethyl)amino]-13-(b...)
Affinity DataEC50:  22nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249687(2,10-Dihydroxy-6-{[3-(hydroxymethyl)benzyl]amino}-...)
Affinity DataEC50:  22nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249691(2,10-Dihydroxy-6-({[4-(hydroxymethyl)pyridin-2-yl]...)
Affinity DataEC50:  22nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249673(2,10-Dihydroxy-6-[(pyridin-3-ylmethyl)amino]-13-(b...)
Affinity DataEC50:  23nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249686(2,10-Dihydroxy-6-[(3-hydroxybenzyl)amino]-13-(beta...)
Affinity DataEC50:  23nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249688(2,10-Dihydroxy-6-{[2-(hydroxymethyl)benzyl]amino}-...)
Affinity DataEC50:  24nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249668(6-(Benzylamino)-2,10-dihydroxy-13-(beta-D-glucopyr...)
Affinity DataEC50:  25nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249693(2,10-Dihydroxy-6-({[4-(hydroxymethyl)pyridin-3-yl]...)
Affinity DataEC50:  25nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249690(2,10-Dihydroxy-6-({[5-(hydroxymethyl)pyridin-2-yl]...)
Affinity DataEC50:  27nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249696(2,10-Dihydroxy-6-({[3-(hydroxymethyl)pyridin-4-yl]...)
Affinity DataEC50:  29nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 74 total ) | Next | Last >>
Jump to: