TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity to the human histamine H3 receptorMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Binding affinity of compound towards rat histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Binding affinity of compound towards rat histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 12.3nMAssay Description:Binding affinity to the human histamine H4 receptorMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [3H]HOCPCA from native CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting m...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Binding affinity to the human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Binding affinity to the human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Binding affinity to the human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of interaction between human KEAP1 Kelch domain/FAM-Nrf2 using Cy5-Nrf2 incubated for 10 to 15 mins by competitive fluorescence polarizati...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of recombinant human His-tagged Keap1 kelch domain (321 to 609 residues) expressed in Escherichia coli BL21(DE3) cells to Cy5-Nrf2 (unknow...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 46nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells by fluorescence polariza...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [3H]HOCPCA from native CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting m...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [3H]HOCPCA from native CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting m...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 52nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 57nMAssay Description:Displacement of [3H]HOCPCA from native CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting m...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 57nMAssay Description:Displacement of [3H]HOCPCA from native CaMK2alpha in rat brain cortical membrane homogenates measured after 1 hr by TopCount scintillation counting m...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair