Affinity DataKi: 0.0270nMAssay Description:Binding affinity to human dopamine D2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0660nMAssay Description:Binding affinity to human dopamine D4 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [125I]-IABN from human recombinant dopamine D3 receptor expressed in HEK293 cell membrane incubated for 60 mins filtration binding as...More data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.290nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.309nMAssay Description:Cataleptogenic effect against cloned human Dopamine receptor D2 in male Sprague-Dawley rats in a bar testMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:In vitro ability to inhibit the binding of [3H]-spiperone to cloned human Dopamine receptor D2 using apomorphine induced climbing test in male Swiss ...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Binding affinity against [3H]-3-PPP labelled sigma sitesMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Binding affinity for dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.468nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.480nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.480nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Florida A&M University
Curated by ChEMBL
Florida A&M University
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]Citalopram from human SERT by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.708nMAssay Description:Cataleptogenic effect against cloned human Dopamine receptor D3 in male Sprague-Dawley rats in a bar testMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:In vitro ability to inhibit the binding of [3H]-7-OH-DPAT to cloned human Dopamine receptor D3 using apomorphine induced climbing test in male Swiss ...More data for this Ligand-Target Pair
Affinity DataKi: 0.720nMAssay Description:Binding affinity to human cloned 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.741nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.760nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.810nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to cloned human Dopamine receptor D2 using apomorphine induced climbing test in male Swiss m...More data for this Ligand-Target Pair
Affinity DataKi: 0.891nMAssay Description:In vitro ability to inhibit the binding of [3H]-spiperone to cloned human Dopamine receptor D2 using apomorphine induced climbing test in male Swiss ...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Florida A&M University
Curated by ChEMBL
Florida A&M University
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]Citalopram from human SERT by liquid scintillation countingMore data for this Ligand-Target Pair