Compile Data Set for Download or QSAR
maximum 50k data
Found 63 with Last Name = 'furugohri' and Initial = 't'
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287299((2S,4S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-thiazol...)
Affinity DataIC50:  0.690nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286907((S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl)-pe...)
Affinity DataIC50:  2.30nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286905((S)-5-Biphenyl-4-yl-4-(1-carboxy-ethylcarbamoyl)-2...)
Affinity DataIC50:  2.80nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286905((S)-5-Biphenyl-4-yl-4-(1-carboxy-ethylcarbamoyl)-2...)
Affinity DataIC50:  2.80nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286906((2S,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286906((2S,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286906((2S,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 (KDR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287301((2R,4S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-thiazol...)
Affinity DataIC50:  3.30nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286908((2R,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50:  5.90nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286908((2R,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50:  5.90nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286906((2S,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50:  5.90nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287304((S)-5-Biphenyl-4-yl-2-phenoxymethyl-4-(1H-tetrazol...)
Affinity DataIC50:  7.40nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50:  7.90nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50:  7.90nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286909((S)-5-Biphenyl-4-yl-4-((R)-1-carboxy-ethylcarbamoy...)
Affinity DataIC50:  8.70nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286909((S)-5-Biphenyl-4-yl-4-((R)-1-carboxy-ethylcarbamoy...)
Affinity DataIC50:  8.70nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287300(2-[(S)-3-Biphenyl-4-yl-2-(4-carboxymethyl-thiazol-...)
Affinity DataIC50:  9.80nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287300(2-[(S)-3-Biphenyl-4-yl-2-(4-carboxymethyl-thiazol-...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214997(CHEMBL439391 | trans-N-(2-(5-chloro-1H-indole-2-ca...)
Affinity DataIC50:  11.3nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214983(CHEMBL391805 | N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214995(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214995(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287297((S)-5-Biphenyl-4-yl-2-phenoxymethyl-4-[(1H-tetrazo...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287302((S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-thiazol-2-y...)
Affinity DataIC50:  58nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403562(CHEMBL2062138 | UK-69578)
Affinity DataIC50:  65nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214988(CHEMBL393873 | trans-N-(2-(5-chloro-1H-indole-2-ca...)
Affinity DataIC50:  86nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287303((S)-5-Biphenyl-4-yl-4-(5-carboxymethyl-[1,3,4]thia...)
Affinity DataIC50:  92nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214986(CHEMBL247732 | N-((1S,2R)-2-(5-chloro-1H-indole-2-...)
Affinity DataIC50: >100nMAssay Description:Inhibition of human factor 2a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286910((S)-5-Biphenyl-4-yl-4-(1-carboxy-3-methylsulfanyl-...)
Affinity DataIC50:  101nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214985(CHEMBL391804 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Affinity DataIC50:  118nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287305((S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-thiazol-2-y...)
Affinity DataIC50:  122nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214987(CHEMBL245679 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Affinity DataIC50:  175nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214998(CHEMBL391593 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Affinity DataIC50:  187nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287298((S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-1H-imidazol...)
Affinity DataIC50:  218nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214999(CHEMBL247525 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Affinity DataIC50:  265nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214992(CHEMBL246915 | cis-N-(2-(5-chloro-1H-indole-2-sulf...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286917((R)-2-[(R)-2-(Carboxymethyl-carbamoyl)-3-(4-pyrazo...)
Affinity DataIC50:  366nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286915(4-(Carboxymethyl-carbamoyl)-2-phenoxymethyl-5-phen...)
Affinity DataIC50:  407nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214986(CHEMBL247732 | N-((1S,2R)-2-(5-chloro-1H-indole-2-...)
Affinity DataIC50:  753nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287296((S)-5-Biphenyl-4-yl-4-(1-carboxymethyl-1H-imidazol...)
Affinity DataIC50:  763nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286916(4-(Carboxymethyl-carbamoyl)-2-(2-methoxy-ethoxymet...)
Affinity DataIC50:  945nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286915(4-(Carboxymethyl-carbamoyl)-2-phenoxymethyl-5-phen...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286914((2R,4R)-4-(Biphenyl-4-yloxy)-4-(carboxymethyl-carb...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286913((Z)-2-[(R)-2-(Carboxymethyl-carbamoyl)-3-(4-pyrazo...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286911(4-(Carboxymethyl-carbamoyl)-2-methyl-5-(5-phenyl-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286912(1-((S)-2-Biphenyl-4-ylmethyl-4-carboxy-5-phenoxy-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286912(1-((S)-2-Biphenyl-4-ylmethyl-4-carboxy-5-phenoxy-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 (KDR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286916(4-(Carboxymethyl-carbamoyl)-2-(2-methoxy-ethoxymet...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214993(CHEMBL247535 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Affinity DataIC50: >1.40E+3nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214990(CHEMBL391594 | trans-N-(2-(5-chloro-1H-indole-2-ca...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 63 total ) | Next | Last >>
Jump to: