TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0140nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0220nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0240nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0240nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0270nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0310nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0470nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0480nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0480nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0570nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0570nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0590nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0590nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0620nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0650nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory effect of the compound against Human ET-A receptorMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Banyu Tsukuba Research Institute
Banyu Tsukuba Research Institute
Affinity DataIC50: 1.60nMAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Banyu Tsukuba Research Institute
Banyu Tsukuba Research Institute
Affinity DataIC50: 2.30nMAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory effect of the compound against porcine ET-A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibitory effect of the compound against Human ET-A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory effect of the compound against porcine ET-A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 5.60nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibitory effect of the compound against Human Endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin B receptorMore data for this Ligand-Target Pair