Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -55.3kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -55.3kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -54.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to A2A adenosine receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -54.0kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -53.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nM ΔG°: -52.8kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -52.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -52.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -52.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -52.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to dopamine D5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nM ΔG°: -51.8kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair