Compile Data Set for Download or QSAR
maximum 50k data
Found 82 with Last Name = 'jin' and Initial = 'tg'
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260952(CHEMBL4104489)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50248628(CHEMBL4072496)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260950(CHEMBL4100387)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260954(CHEMBL4070689)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260951(CHEMBL4077370)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260953(CHEMBL4072044)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260930(CHEMBL4087403)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260947(CHEMBL4095089)
Affinity DataIC50:  37nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399006(CHEMBL2177587)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334366(CHEMBL1643308 | N-(2-aminophenyl)-3-(4-(1-(2-morph...)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260946(CHEMBL4077546)
Affinity DataIC50:  87nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  100nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399005(CHEMBL2177588)
Affinity DataIC50:  140nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260959(CHEMBL4066001)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260961(CHEMBL4064964)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260955(CHEMBL4090079)
Affinity DataIC50:  170nMAssay Description:Inhibition wild type LRRK2 (unknown origin) Ser935 phosphorylation in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399005(CHEMBL2177588)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  220nMAssay Description:Inhibition of HDAC2 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399006(CHEMBL2177587)
Affinity DataIC50:  230nMAssay Description:Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  230nMAssay Description:Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260929(CHEMBL4072962)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399006(CHEMBL2177587)
Affinity DataIC50:  250nMAssay Description:Inhibition of HDAC2 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399005(CHEMBL2177588)
Affinity DataIC50:  270nMAssay Description:Inhibition of HDAC2 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260927(CHEMBL4062035)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260948(CHEMBL4102849)
Affinity DataIC50:  350nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260928(CHEMBL4104570)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260960(CHEMBL4084901)
Affinity DataIC50:  480nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399008(CHEMBL2178223)
Affinity DataIC50:  700nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399005(CHEMBL2177588)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of HDAC5 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399005(CHEMBL2177588)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of HDAC10 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399007(CHEMBL2178221)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399007(CHEMBL2178221)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399008(CHEMBL2178223)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399007(CHEMBL2178221)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399006(CHEMBL2177587)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of HDAC10 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399006(CHEMBL2177587)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of HDAC5 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399008(CHEMBL2178223)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260926(CHEMBL4082225)
Affinity DataIC50:  4.63E+3nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50260949(CHEMBL4066087)
Affinity DataIC50:  4.95E+3nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of HDAC10 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399006(CHEMBL2177587)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399005(CHEMBL2177588)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of HDAC5 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399008(CHEMBL2178223)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399008(CHEMBL2178223)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399006(CHEMBL2177587)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399007(CHEMBL2178221)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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