Affinity DataKi: 15nMAssay Description:The compound was evaluated for the binding affinity against L. casei dTMP synthase using spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of human thymidine phosphorylaseMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of dichloromethotrexate-resistant Lactobacillus casei thymidylate synthase by Dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Reversible competitive inhibition of dichloromethotrexate-resistant Lactobacillus casei thymidylate synthase using 5-mercapto-2'-deoxyuridylate as su...More data for this Ligand-Target Pair
Affinity DataKi: 1.42E+3nMAssay Description:Compound was tested for competitive antagonist of Nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.16E+3nMAssay Description:The compound was tested for competitive antagonist of Nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.77E+4nMAssay Description:The compound was tested for competitive antagonist of Nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 4.11E+4nMAssay Description:The compound was tested for competitive antagonist of Nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of cellular thymidylate synthase activity of mouse fibroblast (L929 TK-) in permeabilised cells.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against dihydrofolate reductase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of cellular thymidylate synthase activity of murine leukemia cell line (L1210) in intact cells.More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against dihydrofolate reductase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Evaluated for the inhibition of thymidylate synthase in intact L1210 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of cellular thymidylate synthase activity of murine leukemia cell line (L1210) in permeabilised cells.More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of cellular thymidylate synthase activity of murine leukemia cell line (L1210) in intact cells.More data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:compound was evaluated for the inhibitory activity against Dihydrofolate reductase in permeabilised L1210 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:compound was evaluated for the inhibitory activity against Dihydrofolate reductase in permeabilised L1210 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of cellular thymidylate synthase activity of mouse fibroblast (L929 TK-) in intact cells.More data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of cellular thymidylate synthase activity of mouse fibroblast (L929 TK-) in permeabilised cells.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of cellular thymidylate synthase activity of mouse fibroblast (L929 TK-) in intact cells.More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:compound was evaluated for the inhibitory activity against Dihydrofolate reductase in permeabilised L1210 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of cellular thymidylate synthase activity of murine leukemia cell line (L1210) in permeabilised cells.More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
State University of New York
Curated by ChEMBL
State University of New York
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Folyl-polyglutamate synthase from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Evaluated for the inhibition of dihydrofolate reductase in L. caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cellular thymidylate synthase activity of murine leukemia cell line (L1210) in permeabilised cells.More data for this Ligand-Target Pair