Found 5 with Last Name = 'corpas-lopez' and Initial = 'v' TargetCytochrome P450 1A2(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in pooled human liver microsomes using phenacetin as substrate preincubated for 30 mins in presence of NADPH followed by substra...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 in pooled human liver microsomes using diclofenac as substrate preincubated for 30 mins in presence of NADPH followed by substra...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in pooled human liver microsomes using midazolam or testosterone as substrate preincubated for 30 mins in presence of NADPH foll...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in pooled human liver microsomes using dextromethorphan as substrate preincubated for 30 mins in presence of NADPH followed by s...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19 in pooled human liver microsomes using (S)-(+)-mephenytoin as substrate preincubated for 30 mins in presence of NADPH followed ...More data for this Ligand-Target Pair
