TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Texas State University-San Marcos
Curated by ChEMBL
Texas State University-San Marcos
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Competitive inhibition of recombinant His-tagged CHK1 (unknown origin) expressed in baculovirus expression system using CDC25C and ATP as substrate a...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of cathepsin D.More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
H�Pital Kirchberg
Curated by ChEMBL
H�Pital Kirchberg
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 106nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 756nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of cathepsin D.More data for this Ligand-Target Pair
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
H�Pital Kirchberg
Curated by ChEMBL
H�Pital Kirchberg
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
H�Pital Kirchberg
Curated by ChEMBL
H�Pital Kirchberg
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of cathepsin D.More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
H�Pital Kirchberg
Curated by ChEMBL
H�Pital Kirchberg
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of cathepsin D.More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.79E+3nMAssay Description:Inhibition of cathepsin D.More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair