TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 103nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 137nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 141nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrateMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair