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Found 33 with Last Name = 'kozak' and Initial = 'w'
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  0.0650nMAssay Description:Inhibition of STS in human MCF7 cells assessed as reduction in [3H]estradiol and [3H]estrone formation using [3H]estrone sulfate as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  0.0650nMAssay Description:Inhibition of STS in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50604012(CHEMBL5199004)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50604011(CHEMBL5205557)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50604009(CHEMBL5170413)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50604008(CHEMBL5179747)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50604010(CHEMBL5169672)
Affinity DataIC50:  3nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116170(CHEMBL3612355)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human STS transfected in CHO cells using MUS as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116171(CHEMBL3612354)
Affinity DataIC50:  8nMAssay Description:Inhibition of human placenta STSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50604012(CHEMBL5199004)
Affinity DataIC50:  37nMAssay Description:Inhibition of human placental STS using [3H]E1S as substrate incubated for 3 hrs by radioisotope enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50051829(4-methyl-2-oxo-2H-chromen-7-yl sulfamate | CHEMBL1...)
Affinity DataIC50:  380nMAssay Description:Inhibition of STS in human MCF7 cells assessed as reduction in [3H]estradiol and [3H]estrone formation using [3H]estrone sulfate as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116187(CHEMBL3612348)
Affinity DataIC50:  860nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116173(CHEMBL3612353)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288960(CHEMBL156638 | N-[(R)-2-(1H-Indol-3-yl)-1-mercapto...)
Affinity DataIC50:  1.70E+3nMAssay Description:Compound was evaluated for inhibition of Endothelin-converting enzyme 1 partially purified from porcine primary aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288964(CHEMBL156740 | Thiophene-2-carboxylic acid [(R)-2-...)
Affinity DataIC50:  5.20E+3nMAssay Description:Compound was evaluated for inhibition of Endothelin-converting enzyme 1 partially purified from porcine primary aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288958(2-Biphenyl-4-yl-N-((R)-1-mercaptomethyl-2-pyridin-...)
Affinity DataIC50:  5.20E+3nMAssay Description:Compound was evaluated for inhibition of Endothelin-converting enzyme 1 partially purified from porcine primary aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288957(4-[(R)-2-(1H-Indol-3-yl)-1-mercaptomethyl-ethylcar...)
Affinity DataIC50:  5.40E+3nMAssay Description:Compound was evaluated for inhibition of Endothelin-converting enzyme 1 partially purified from porcine primary aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116183(CHEMBL3612349)
Affinity DataIC50:  5.51E+3nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288963(2-(4-Benzyloxy-phenyl)-N-[(R)-2-(1H-indol-3-yl)-1-...)
Affinity DataIC50:  6.50E+3nMAssay Description:Compound was evaluated for inhibition of Endothelin-converting enzyme 1 partially purified from porcine primary aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288961(1-(2-Biphenyl-4-yl-acetyl)-piperidine-4-carboxylic...)
Affinity DataIC50:  6.50E+3nMAssay Description:Compound was evaluated for inhibition of Endothelin-converting enzyme 1 partially purified from porcine primary aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116189(CHEMBL3612307)
Affinity DataIC50:  6.77E+3nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116193(CHEMBL3612304)
Affinity DataIC50:  7.04E+3nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288962(CHEMBL156964 | N-[(R)-2-(1H-Indol-3-yl)-1-mercapto...)
Affinity DataIC50:  7.70E+3nMAssay Description:Compound was evaluated for inhibition of Endothelin-converting enzyme 1 partially purified from porcine primary aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116195(CHEMBL3612303)
Affinity DataIC50:  7.76E+3nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288959(CHEMBL421819 | N-((R)-1-Mercaptomethyl-2-phenyl-et...)
Affinity DataIC50:  7.80E+3nMAssay Description:Compound was evaluated for inhibition of Endothelin-converting enzyme 1 partially purified from porcine primary aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116190(CHEMBL3612306)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116188(CHEMBL3612308)
Affinity DataIC50:  2.69E+4nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116196(CHEMBL3612302)
Affinity DataIC50:  3.38E+4nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116182(CHEMBL3612350)
Affinity DataIC50:  7.43E+4nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116192(CHEMBL3612305)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116175(CHEMBL3612352)
Affinity DataIC50:  8.88E+4nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Gdask University Of Technology

Curated by ChEMBL
LigandPNGBDBM50116180(CHEMBL3612351)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of human placenta STS using NPS as substrate after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed