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Found 466 with Last Name = 'cheung' and Initial = 'ws'
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273022(1-(2,3-dimethylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273058(CHEMBL457186 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273024(1-(3,4-difluorophenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272980(CHEMBL455958 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272856(CHEMBL497485 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272979(CHEMBL509968 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272900(1-(2-bromophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b]...)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272982(1-(2-isopropylphenyl)-N-(3-oxo-3,4-dihydro-2H-benz...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272983(1-(2-bromo-3-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272858(1-(3-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  84nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272899(1-(2-chlorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272859(1-(3-chlorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  97nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273021(1-(3-chloro-2-methylphenyl)-N-(3-oxo-3,4-dihydro-2...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272981(1-(2-ethylphenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b]...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273057(1-(3,5-difluorophenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataKi:  137nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273023(1-(4-tert-butylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataKi:  142nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272897(CHEMBL455926 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataKi:  225nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273025(1-(3,4-dimethylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataKi:  314nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272898(1-(2-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  1.47E+3nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193240(US9193736, 164)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM193202(US9193736, 121)
Affinity DataIC50: <1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193207(US9193736, 127)
Affinity DataIC50: <1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193218(US9193736, 139)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193221(US9193736, 143)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193222(US9193736, 144)
Affinity DataIC50: <1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193225(US9193736, 148)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193226(US9193736, 149)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193236(US9193736, 160)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193240(US9193736, 164)
Affinity DataIC50: <1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193246(US9193736, 170)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193248(US9193736, 172)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193249(US9193736, 174)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM193225(US9193736, 148)
Affinity DataIC50:  1nMpH: 7.8Assay Description:Rat recombinant PDE10a (rPDE10a) was expressed in Sf9 cells using a recombinant rPDE10a baculovirus construct. Cells were harvested after 48 h of inf...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM193226(US9193736, 149)
Affinity DataIC50:  1nMpH: 7.8Assay Description:Rat recombinant PDE10a (rPDE10a) was expressed in Sf9 cells using a recombinant rPDE10a baculovirus construct. Cells were harvested after 48 h of inf...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193108(US9193736, 24)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193112(US9193736, 28)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193114(US9193736, 30)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193115(US9193736, 31)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193121(US9193736, 37)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193125(US9193736, 41)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193126(US9193736, 42)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193141(US9193736, 57)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193144(US9193736, 60)
Affinity DataIC50: <1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193145(US9193736, 61)
Affinity DataIC50: <1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193148(US9193736, 64)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193161(US9193736, 77)
Affinity DataIC50: <1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193164(US9193736, 80)
Affinity DataIC50: <1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193165(US9193736, 81)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193166(US9193736, 82)
Affinity DataIC50: <1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM193167(US9193736, 83)
Affinity DataIC50:  1nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...More data for this Ligand-Target Pair
In DepthDetails US Patent
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