TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataKi: 0.730nMAssay Description:Competitive inhibition of human PREP using Suc-GP-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Competitive inhibition of human FAP using Suc-GP-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataKi: 3.10E+3nMAssay Description:Competitive inhibition of human PREP using Suc-GP-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 4.30E+3nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:Competitive inhibition of human recombinant DPP4 using AP-pNA as substrate preincubated for 30 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Competitive inhibition of human recombinant DPP4 using AP-pNA as substrate preincubated for 30 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 6.30E+3nMAssay Description:Competitive inhibition of human recombinant DPP4 using AP-pNA as substrate preincubated for 30 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataKi: 8.40E+3nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 6.10E+4nMAssay Description:Competitive inhibition of human recombinant DPP4 using AP-pNA as substrate preincubated for 30 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 1.42E+5nMAssay Description:Competitive inhibition of human recombinant DPP4 using AP-pNA as substrate preincubated for 30 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.260nMpH: 2.0Assay Description:The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human DPP4 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Inhibition of human DPP9 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.350nMpH: 2.0Assay Description:The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq...More data for this Ligand-Target Pair
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human DPP4 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair