BindingDB PrimarySearch_ki

Found 1060 with Last Name = 'andreotti' and Initial = 'd'

Sodium-dependent serotonin transporter(MOUSE)
Glaxosmithkline

Curated by ChEMBL

PNG

BDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)

Ki: 1.58nMAssay Description:Displacement of [3H]-citalopram from SERT in mouse cortex after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

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Details Article PubMed

Sodium-dependent noradrenaline transporter(MOUSE)
Glaxosmithkline

Curated by ChEMBL

PNG

BDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)

Ki: 1.58nMAssay Description:Displacement of [3H]nisoxetine from NET in mouse brainMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

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Details Article PubMed

Transporter(Rattus norvegicus (rat))
Glaxosmithkline

Curated by ChEMBL

PNG

BDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)

Ki: 2.51nMAssay Description:Displacement of [3H]nisoxetine from NET in rat hippocampus after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair

Reactome pathway
UniProtKB/TrEMBL
GoogleScholar

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Details Article PubMed

Sodium-dependent dopamine transporter(MOUSE)
Glaxosmithkline

Curated by ChEMBL

PNG

BDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)

Ki: 10nMAssay Description:Displacement of [3H]WIN-35428 from DAT in mouse brainMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

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Details Article PubMed

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612208(CHEMBL5284027)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612209(CHEMBL5288427)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612225(CHEMBL5286893)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612226(CHEMBL5281154)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612227(CHEMBL5289675)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612206(CHEMBL5277668)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612231(CHEMBL5280373)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612206(CHEMBL5277668)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612225(CHEMBL5286893)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612226(CHEMBL5281154)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612230(CHEMBL5270706)

IC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612230(CHEMBL5270706)

IC50: 0.300nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612207(CHEMBL5274608)

IC50: 0.400nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612205(CHEMBL5279036)

IC50: 0.440nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612209(CHEMBL5288427)

IC50: 0.530nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612208(CHEMBL5284027)

IC50: 0.700nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612229(CHEMBL5280577)

IC50: 0.800nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612223(CHEMBL5279816)

IC50: 0.820nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612207(CHEMBL5274608)

IC50: 0.880nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612230(CHEMBL5270706)

IC50: 1nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pS1292 phosphorylation incubated for 2 hrs by MSD analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612227(CHEMBL5289675)

IC50: 1nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612230(CHEMBL5270706)

IC50: 1.10nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pSer935 phosphorylation incubated for 2 hrs by HTRF analys...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612226(CHEMBL5281154)

IC50: 1.20nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pS1292 phosphorylation incubated for 2 hrs by MSD analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612230(CHEMBL5270706)

IC50: 1.5nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pSer935 phosphorylation incubated for 2 hrs by immunoblott...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612221(CHEMBL5289513)

IC50: 1.60nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612231(CHEMBL5280373)

IC50: 1.70nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pS1292 phosphorylation incubated for 2 hrs by MSD analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612210(CHEMBL5271931)

IC50: 2.40nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612226(CHEMBL5281154)

IC50: 2.40nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pSer935 phosphorylation incubated for 2 hrs by HTRF analys...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612231(CHEMBL5280373)

IC50: 2.5nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pSer935 phosphorylation incubated for 2 hrs by immunoblott...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612219(CHEMBL5286615)

IC50: 2.60nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612212(CHEMBL5288038)

IC50: 3nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612231(CHEMBL5280373)

IC50: 3.10nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pSer935 phosphorylation incubated for 2 hrs by HTRF analys...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612230(CHEMBL5270706)

IC50: 4.70nMAssay Description:Inhibition human LRRK2 G2019S mutant expressed in human HEK293 assessed as Rab10 substrate phosphorylation at Threonine 73 residue incubated for 2 hr...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612219(CHEMBL5286615)

IC50: 5.70nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612211(CHEMBL5266676)

IC50: 6nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612231(CHEMBL5280373)

IC50: 6.60nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50269801(CHEMBL4100294)

IC50: 7.90nMAssay Description:Inhibition of LRRK2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article PubMed

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50269809(CHEMBL4077195)

IC50: 7.90nMAssay Description:Inhibition of human LRRK2 using RLGRDKYKTLRQIRQ as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article PubMed

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50269824(CHEMBL4098650)

IC50: 7.90nMAssay Description:Inhibition of LRRK2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article PubMed

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50269800(CHEMBL4068065)

IC50: 7.90nMAssay Description:Inhibition of LRRK2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article PubMed

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612206(CHEMBL5277668)

IC50: 8.30nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pSer935 phosphorylation incubated for 2 hrs by HTRF analys...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612205(CHEMBL5279036)

IC50: 9nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50612206(CHEMBL5277668)

IC50: 9.20nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pS1292 phosphorylation incubated for 2 hrs by MSD analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM482159(BDBM50401284 | GSK2578215A)

IC50: 10nMAssay Description:Inhibition of LRRK2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50269810(CHEMBL4101126)

IC50: 10nMAssay Description:Inhibition of LRRK2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid Patents Similars

Details Article PubMed

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50269816(CHEMBL4072195)

IC50: 10nMAssay Description:Inhibition of LRRK2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article PubMed

Displayed 1 to 50 (of 1060 total ) | Next | Last >>

Filter my 1060 hits

Targets 17▿
- Leucine-rich repeat serine/threonine-protein kinase 2 497
- Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] 335
- Corticotropin-releasing factor receptor 1 67
- Cytochrome P450 2D6 27
- Cytochrome P450 3A4 26
- Cytochrome P450 1A2 25
- Cytochrome P450 2C19 25
- Cytochrome P450 2C9 24
- DNA gyrase subunit A/B 12
- Potassium voltage-gated channel subfamily H member 2 12
- Sodium channel protein type 5 subunit alpha 4
- Sodium-dependent serotonin transporter 1
- DNA topoisomerase 2-alpha 1
- SRSF protein kinase 3 1
- Sodium-dependent noradrenaline transporter 1
- Sodium-dependent dopamine transporter 1
- Transporter 1
- ...
Publications 9▿
- US Patent US11427558 (2022) 670
- J Med Chem 53: 5801-12 (2010) 71
- J Med Chem 51: 7273-86 (2009) 44
- Bioorg Med Chem Lett 20: 4566-8 (2010) 39
- Bioorg Med Chem Lett 27: 4034-4038 (2017) 36
- J Med Chem 53: 4989-5001 (2010) 29
- J Med Chem 51: 7370-9 (2009) 23
- Bioorg Med Chem Lett 29: 1407-1412 (2019) 21
- Bioorg Med Chem Lett 22: 5625-9 (2012) 1
Institutions 3▿
- Escape Bio 670
- Glaxosmithkline 228
- Neurodegeneration Dpu 36
Affinity: 0.20 to 2.1E+5 nM▿
- Ki 4
- IC50 1055
- Kd 1
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 17