TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of mTOR assessed as inhibition of phosphorylation of 4EBP1 by Lantha-Screen enzyme assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ALK Tyr1604 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mTOR assessed as inhibition of phosphorylation of 4EBP1 by Lantha-Screen enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK Tyr1604 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair