TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human recombinant PDE4D using [3H]cAMP as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human recombinant PDE4A using [3H]cAMP as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant PDE4C using [3H]cAMP as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of PDE4A (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of AChE in rat brain HippocampusMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of PDE4A (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of AChE in rat brain cortexMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 287nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant PDE4D3 using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of PDE4A (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of AChE in rat brain HippocampusMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of AChE in rat brain cortexMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant PDE4D3 using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant PDE4C using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of PDE4C (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant PDE4B1 using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of electric eel AChE using acetylcholine iodide as a substrate incubated for 10 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of AChE in rat brain StriatumMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of PDE4C (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human recombinant PDE4D3 using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of PDE4C (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of AChE in rat brain CerebellumMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of AChE in rat brain CerebellumMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of human recombinant PDE4D3 using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: 3.46E+4nMAssay Description:Inhibition of AChE in rat brain StriatumMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: 3.53E+4nMAssay Description:Inhibition of human recombinant PDE4D3 using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of AChE in rat brain CerebellumMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of AChE in rat brain HippocampusMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of AChE in rat brain StriatumMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Universidade Federal De Mato Grosso Do Sul
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of AChE in rat brain cortexMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
University Of S£O Paulo
Curated by ChEMBL
University Of S£O Paulo
Curated by ChEMBL
Affinity DataEC50: 7.20nMAssay Description:Agonist activity at human TRPV1 expressed in HEK293T cells assessed as increase in Ca2+ transport incubated for 5 mins by calcium-5 fluorescence dye-...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
University Of S£O Paulo
Curated by ChEMBL
University Of S£O Paulo
Curated by ChEMBL
Affinity DataEC50: 4.62E+3nMAssay Description:Agonist activity at human TRPV1 expressed in HEK293T cells assessed as increase in Ca2+ transport incubated for 5 mins by calcium-5 fluorescence dye-...More data for this Ligand-Target Pair