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Found 140 with Last Name = 'bartizal' and Initial = 'kf'
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038093((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.0400nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038102((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.0400nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038087((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.0600nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038138((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.0700nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038092((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.0900nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038089((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.120nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038120((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.130nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038123((6R,7R)-4,7-Dihydroxy-1-(5-methyl-6-phenyl-hexyl)-...)
Affinity DataIC50:  0.140nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038122((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.160nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038121((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.170nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038091((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.190nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038151((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.190nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038125((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.200nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038090((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.200nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038119((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.210nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038096((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.230nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038103((6R,7R)-6-((E)-(4S,6S)-4,6-Dimethyl-oct-2-enoyloxy...)
Affinity DataIC50:  0.240nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038114((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.260nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038135((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.280nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038102((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.280nMAssay Description:compound required to inhibit 50% activity of yeast squalene synthase enzyme (YESS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038089((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.300nMAssay Description:compound required to inhibit 50% activity of yeast squalene synthase enzyme (YESS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038127((6R,7R)-1-(4-Acetoxy-5-methyl-6-phenyl-hexyl)-4,7-...)
Affinity DataIC50:  0.370nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038128((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.380nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038104((6R,7R)-6-((E)-(4S,6S)-4,6-Dimethyl-oct-2-enoyloxy...)
Affinity DataIC50:  0.420nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038101((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.520nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038093((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.640nMAssay Description:compound required to inhibit 50% activity of yeast squalene synthase enzyme (YESS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038088((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.660nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038144((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.75nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038154((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.790nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038129((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.800nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038111((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.800nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038106((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.800nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038149((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.810nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038106((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.960nMAssay Description:Compound required to inhibit 50% activity of yeast squalene synthase enzyme (YESS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038097((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  1nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289910(1N-[21-(2-aminoethoxy)-3-(3-amino-1-hydroxypropyl)...)
Affinity DataIC50:  1nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038131((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  1.10nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038155((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  1.20nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289923(1N-[21-(2-aminoethoxy)-3-[3-(1,4-diaminobutylcarbo...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038117((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  1.60nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038107((6R,7R)-6-((4R,6S)-4,6-Dimethyl-octanoyloxy)-4,7-d...)
Affinity DataIC50:  1.80nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038130((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  2nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038152((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  2nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038099((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  2.30nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289914(1N-[21-(2-aminoethoxy)-3-[3-(1,5-diaminopentylcarb...)
Affinity DataIC50:  3nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038143((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  3nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289922(1N-[3-[3-(1,4-diaminobutylcarboxamido)-1-hydroxypr...)
Affinity DataIC50:  3nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038146((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  3.20nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038097((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  3.20nMAssay Description:compound required to inhibit 50% activity of yeast squalene synthase enzyme (YESS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038139((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  3.40nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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