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Found 711 with Last Name = 'bauer' and Initial = 'r'
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160194(3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3-dihydr...)
Affinity DataKi:  28nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160192(8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-7,8-dihydr...)
Affinity DataKi:  28nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160172(3-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-2,3-dihyd...)
Affinity DataKi:  35nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160173(3-[1-(2-Iodo-phenyl)-meth-(E)-ylidene]-2,3-dihydro...)
Affinity DataKi:  76nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160188(3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-1,2,3,9-te...)
Affinity DataKi:  90nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160193(3-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-1,2,3,9-t...)
Affinity DataKi:  110nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160171(3-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-1-ethyl-1...)
Affinity DataKi:  140nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160195(3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-1-butyl-1,...)
Affinity DataKi:  250nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160179(8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3-dimeth...)
Affinity DataKi:  260nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160167(8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3-dimeth...)
Affinity DataKi:  270nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160190(8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-3-cyclopro...)
Affinity DataKi:  290nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160170(CHEMBL360560 | [3-[1-(2-Bromo-phenyl)-meth-(E)-yli...)
Affinity DataKi:  310nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160180(1-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3,5,6,7,...)
Affinity DataKi:  350nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160168(3-[1-(2-Ethyl-phenyl)-meth-(E)-ylidene]-2,3-dihydr...)
Affinity DataKi:  360nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160187(3-[1-(3,4-Dichloro-phenyl)-meth-(E)-ylidene]-1,2,3...)
Affinity DataKi:  720nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160182(9-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-8,9-dihydr...)
Affinity DataKi:  820nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50410084(CHEMBL2113024)
Affinity DataKi:  830nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160174(3-[1-(2-Chloro-4-fluoro-phenyl)-meth-(E)-ylidene]-...)
Affinity DataKi:  930nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160191(8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-3-tert-but...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160177(3-[1-(2-Fluoro-phenyl)-meth-(E)-ylidene]-1,2,3,9-t...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160169(3-[1-(2-Ethyl-phenyl)-meth-(E)-ylidene]-1,2,3,9-te...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160189(CHEMBL434151 | {3-Chloro-4-[1,2-dihydro-9H-pyrrolo...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160184(3-[1-(2-Trifluoromethyl-phenyl)-meth-(E)-ylidene]-...)
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160186(3-[1-(2,4-Dichloro-phenyl)-meth-(E)-ylidene]-1,2,3...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160166(3-[1-(2,6-Dichloro-phenyl)-meth-(E)-ylidene]-1,2,3...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160176(3-[1-Biphenyl-2-yl-meth-(E)-ylidene]-1,2,3,9-tetra...)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160178(3-[1-(2-Trifluoromethoxy-phenyl)-meth-(E)-ylidene]...)
Affinity DataKi:  3.20E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160185(3-[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-2,3-dihy...)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160183(3-[1-(2-Ethoxy-phenyl)-meth-(E)-ylidene]-1,2,3,9-t...)
Affinity DataKi:  4.50E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160175(3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3-dihydr...)
Affinity DataKi:  6.10E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma Gmbh And

Curated by ChEMBL
LigandPNGBDBM50160196(3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-1-(4-fluor...)
Affinity DataKi:  7.90E+3nMAssay Description:Binding affinity measured for human C-C chemokine receptor type 3 expressed on human K562 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM603024(1-Ethyl-7-[[(1S)-1-[4- [(1R/S)-1-(4-prop-2- enoylp...)
Affinity DataIC50:  0nMAssay Description:IDH1-R132H, IDH1-R132C, IDH2-R172K and IDH2-R140Q mutant enzymes catalyze the conversion of αKG to 2HG. 2HG is analyzed using in-line solid phas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM600744(US11629156, Example 12)
Affinity DataIC50:  0nMAssay Description:IDH1-R132H, IDH1-R132C, IDH2-R172K and IDH2-R140Q mutant enzymes catalyze the conversion of αKG to 2HG. 2HG is analyzed using in-line solid phas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Cresset

Curated by ChEMBL
LigandPNGBDBM50113476(CHEMBL3603923 | US10246432, Example 17 | US1058411...)
Affinity DataIC50:  0.501nMAssay Description:Inhibition of mGLU5 (unknown origin)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50335827((6R,12aR)6-(2,4-Dichlorophenyl)-2-ethyl-2,3,6,7,12...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant PDE5A-mediated hydrolysis of cGMP after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Cresset

Curated by ChEMBL
LigandPNGBDBM50391946(CHEMBL2147763)
Affinity DataIC50:  2nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50335827((6R,12aR)6-(2,4-Dichlorophenyl)-2-ethyl-2,3,6,7,12...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant PDE5 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Cresset

Curated by ChEMBL
LigandPNGBDBM50391948(CHEMBL2147767)
Affinity DataIC50:  2nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Cresset

Curated by ChEMBL
LigandPNGBDBM50505077(CHEMBL4588064)
Affinity DataIC50:  2nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM497343(7-[[(1S)-1-[4-[2- Cyclopropyl-1-(4-prop-2- enoylpi...)
Affinity DataIC50:  2.49nMAssay Description:IDH1-R132H, IDH1-R132C, IDH2-R172K and IDH2-R140Q mutant enzymes catalyze the conversion of αKG to 2HG. 2HG is analyzed using in-line solid phas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM497343(7-[[(1S)-1-[4-[2- Cyclopropyl-1-(4-prop-2- enoylpi...)
Affinity DataIC50:  2.49nMAssay Description:IDH1-R132H, IDH1-R132C, IDH2-R172K and IDH2-R140Q mutant enzymes catalyze the conversion of αKG to 2HG. 2HG is analyzed using in-line solid phas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM497343(7-[[(1S)-1-[4-[2- Cyclopropyl-1-(4-prop-2- enoylpi...)
Affinity DataIC50:  2.49nMAssay Description:IDH1-R132H, IDH1-R132C, IDH2-R172K and IDH2-R140Q mutant enzymes catalyze the conversion of αKG to 2HG. 2HG is analyzed using in-line solid phas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM497343(7-[[(1S)-1-[4-[2- Cyclopropyl-1-(4-prop-2- enoylpi...)
Affinity DataIC50:  2.76nMAssay Description:IDH1-R132H, IDH1-R132C, IDH2-R172K and IDH2-R140Q mutant enzymes catalyze the conversion of αKG to 2HG. 2HG is analyzed using in-line solid phas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM497343(7-[[(1S)-1-[4-[2- Cyclopropyl-1-(4-prop-2- enoylpi...)
Affinity DataIC50:  2.76nMAssay Description:IDH1-R132H, IDH1-R132C, IDH2-R172K and IDH2-R140Q mutant enzymes catalyze the conversion of αKG to 2HG. 2HG is analyzed using in-line solid phas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM497343(7-[[(1S)-1-[4-[2- Cyclopropyl-1-(4-prop-2- enoylpi...)
Affinity DataIC50:  2.76nMAssay Description:IDH1-R132H, IDH1-R132C, IDH2-R172K and IDH2-R140Q mutant enzymes catalyze the conversion of αKG to 2HG. 2HG is analyzed using in-line solid phas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant PDE5A-mediated hydrolysis of cGMP after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Cresset

Curated by ChEMBL
LigandPNGBDBM50391938(CHEMBL2147845)
Affinity DataIC50:  3nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Cresset

Curated by ChEMBL
LigandPNGBDBM50113472(CHEMBL3603919 | US10246432, Example 2 | US10584111...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of mGLU5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM497335(7-[[(1S)-1-[4-[(1S)-2- cyclopropyl-1-(4-prop-2- en...)
Affinity DataIC50:  3.71nMAssay Description:IDH1-R132H, IDH1-R132C, IDH2-R172K and IDH2-R140Q mutant enzymes catalyze the conversion of αKG to 2HG. 2HG is analyzed using in-line solid phas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM497335(7-[[(1S)-1-[4-[(1S)-2- cyclopropyl-1-(4-prop-2- en...)
Affinity DataIC50:  3.71nMAssay Description:IDH1-R132H, IDH1-R132C, IDH2-R172K and IDH2-R140Q mutant enzymes catalyze the conversion of αKG to 2HG. 2HG is analyzed using in-line solid phas...More data for this Ligand-Target Pair
In DepthDetails US Patent
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