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Found 731 with Last Name = 'benowitz' and Initial = 'a'
TargetPeptide deformylase(Escherichia coli)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535516(CHEMBL4542964)
Affinity DataKi:  60nMAssay Description:Inhibition of Escherichia coli PDFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535514(CHEMBL4458398)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535513(CHEMBL4572153)
Affinity DataIC50:  1nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535505(CHEMBL4462876)
Affinity DataIC50:  1nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535509(CHEMBL4457234)
Affinity DataIC50:  1nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535500(CHEMBL4568739)
Affinity DataIC50:  2nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535497(CHEMBL4466084)
Affinity DataIC50:  2nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535515(CHEMBL4559778)
Affinity DataIC50:  2nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535518(CHEMBL4448951)
Affinity DataIC50:  2nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535512(CHEMBL4434997)
Affinity DataIC50:  2nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535508(CHEMBL4518477)
Affinity DataIC50:  2nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535504(CHEMBL4565584)
Affinity DataIC50:  3nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545382(CHEMBL4646450)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535511(CHEMBL4447270)
Affinity DataIC50:  5nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545379(CHEMBL4645010)
Affinity DataIC50:  5nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535501(CHEMBL4435970)
Affinity DataIC50:  5nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535499(CHEMBL4437963)
Affinity DataIC50:  6nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545380(CHEMBL4645458)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545383(CHEMBL4636355)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545382(CHEMBL4646450)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human CDK4/cyclin-D1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535503(CHEMBL4454464)
Affinity DataIC50:  10nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535506(CHEMBL4440847)
Affinity DataIC50:  11nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535502(GSK-1322322B | GSK1322322 | GSK1322322B | Lanopepd...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545379(CHEMBL4645010)
Affinity DataIC50:  13nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444582(CHEMBL3099715)
Affinity DataIC50:  15nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535498(CHEMBL4435803)
Affinity DataIC50:  16nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545383(CHEMBL4636355)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545380(CHEMBL4645458)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG1/S-specific cyclin-D2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CDK6/cyclin-D2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545381(CHEMBL4649032)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535510(CHEMBL4471518)
Affinity DataIC50:  18nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535507(CHEMBL4547624)
Affinity DataIC50:  20nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545384(CHEMBL4548417)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545378(CHEMBL4638298)
Affinity DataIC50:  32nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545376(CHEMBL4638166)
Affinity DataIC50:  32nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545377(CHEMBL4640158)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545381(CHEMBL4649032)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545384(CHEMBL4548417)
Affinity DataIC50:  50nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM621246(US11771711, Example 2)
Affinity DataIC50:  54nMAssay Description:This assay used Scintillation Proximity technology in a signal increase format to evaluate the potency of compounds. Full-length human DNMT1, hemi-me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA (cytosine-5)-methyltransferase 1 [601-1600](Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491448(US10975056, Example 422 | US11771711, Reference co...)
Affinity DataIC50:  79nMAssay Description:This assay used Scintillation Proximity technology in a signal increase format to evaluate the potency of compounds. Human truncated DNMT1(601-1600),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491120((R)-2-((3,5-dicyano-6-(dimethylamino)-4-ethylpyrid...)
Affinity DataIC50:  89nMAssay Description:This assay used Scintillation Proximity technology in a signal increase format to evaluate the potency of compounds. Full-length human DNMT1, hemi-me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM621248(4-(2-amino-1-((3,5-dicyano-6-(dimethylamino)-4-eth...)
Affinity DataIC50:  107nMAssay Description:This assay used Scintillation Proximity technology in a signal increase format to evaluate the potency of compounds. Full-length human DNMT1, hemi-me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545378(CHEMBL4638298)
Affinity DataIC50:  126nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491224(US10975056, Example 168 | US11771711, Reference co...)
Affinity DataIC50:  156nMAssay Description:This assay used Scintillation Proximity technology in a signal increase format to evaluate the potency of compounds. Full-length human DNMT1, hemi-me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptide deformylase(Staphylococcus aureus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50535517(CHEMBL4474270)
Affinity DataIC50:  158nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545377(CHEMBL4640158)
Affinity DataIC50:  158nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545376(CHEMBL4638166)
Affinity DataIC50:  200nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
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