Affinity DataKi: 5.90nMAssay Description:Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 101nMAssay Description:Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 157nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 205nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 246nMAssay Description:Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 259nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 288nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 355nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 404nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Displacement of 125-I echistatin from Vitronectin receptor (alpha v beta3)More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nMAssay Description:Mixed type inhibition of Trypanosoma brucei TR using varying levels of trypanothione disulfide assessed as inhibition constant for enzyme-inhibitor c...More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Mixed type inhibition of Trypanosoma brucei TR using varying levels of trypanothione disulfide assessed as inhibition constant for enzyme-inhibitor c...More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Noncompetitive inhibition of Trypanosoma brucei TR using varying levels of trypanothione disulfide by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+3nMAssay Description:Mixed type inhibition of Trypanosoma brucei TR using varying levels of trypanothione disulfide assessed as inhibition constant for enzyme-substrate-i...More data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase assessed as reduction in NADPH consumption using varying levels of trypanothione disulfide as...More data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Mixed type inhibition of Trypanosoma brucei TR using varying levels of trypanothione disulfide assessed as inhibition constant for enzyme-substrate-i...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+3nMAssay Description:Mixed-type inhibition of Trypanosoma cruzi trypanothione reductase assessed as reduction in NADPH consumption using varying levels of trypanothione d...More data for this Ligand-Target Pair
Affinity DataKi: 6.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase assessed as reduction in NADPH consumption using varying levels of trypanothione disulfide as...More data for this Ligand-Target Pair
Affinity DataKi: 2.24E+4nMAssay Description:Non-competitive inhibition of Trypanosoma cruzi trypanothione reductase assessed as reduction in NADPH consumption using varying levels of trypanothi...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 0.0352nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 0.177nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 0.253nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 0.265nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman methodMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human recombinant acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman methodMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum - University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human recombinant acetylcholinesteraseMore data for this Ligand-Target Pair