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Found 1478 with Last Name = 'bhatia' and Initial = 'p'
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177063(3-(4-Bromo-phenyl)-9-dimethylamino-3H-pyrido[3',2'...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150141(2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity tested on HEK293 cells co-transfected with human D4.4 receptor using [3H]spiperone as a radioligand in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177097(9-Dimethylamino-3-p-tolyl-3H-pyrido[3',2':4,5]thie...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity towards human D4.4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50471340(CHEMBL317912)
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity towards alpha-2B adrenergic receptor of rat neonatal lung in radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150143(2-[4-(2,5-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity tested on HEK293 cells co-transfected with human D4.4 receptor using [3H]spiperone as a radioligand in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177065(9-Dimethylamino-3-(2,4-dimethyl-phenyl)-3H-pyrido[...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177076(3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145078(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177053(9-Dimethylamino-3-(4-ethyl-phenyl)-3H-pyrido[3',2'...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177055(9-Dimethylamino-3-(3-ethyl-phenyl)-3H-pyrido[3',2'...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193321((Z)-1-(3,5-difluorophenyl)-3-(4-pyridin-2-ylpipera...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193331((E)-1-(3,4-dichlorophenyl)-3-(4-pyridin-2-ylpipera...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193296((Z)-1-(3-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193330((E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)pr...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177057(9-Dimethylamino-3-(4-trifluoromethyl-phenyl)-3H-py...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177078(9-Dimethylamino-3-(4-fluoro-phenyl)-3H-pyrido[3',2...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145081(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145081(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50471340(CHEMBL317912)
Affinity DataKi:  8.70nMAssay Description:In vitro binding affinity towards alpha-2A adrenergic receptor of human clone in radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145076(2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  9.60nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145076(2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  9.60nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177081(3-(2,4-Dichloro-phenyl)-9-dimethylamino-3H-pyrido[...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193290((E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(o-tolyl)pr...)
Affinity DataKi:  11.4nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193361((Z)-1-(4-chloro-3-methylphenyl)-3-(4-pyridin-2-ylp...)
Affinity DataKi:  11.6nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50118703(CHEMBL109783 | N-[5-(4,5-Dihydro-1H-imidazol-2-yl)...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity towards alpha-1A adrenergic receptor of rat submaxillary gland in radioligand binding assayMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193307((E)-1-(3-chlorophenyl)-3-(4-pyridin-2-ylpiperazin-...)
Affinity DataKi:  13.5nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193350((E)-1-(3-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-...)
Affinity DataKi:  13.9nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193378((E)-1-(4-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-...)
Affinity DataKi:  14.2nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145084(2-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  14.8nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145084(2-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  14.8nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193311((Z)-1-(4-chlorophenyl)-3-(3',4',5',6'-tetrahydro-2...)
Affinity DataKi:  19.4nMAssay Description:Displacement of [3H]PIPAT from human recombinant D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193357((Z)-4-[1-methoxyimino-3-(4-pyridin-2-ylpiperazin-1...)
Affinity DataKi:  20.1nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145072(2-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataKi:  20.4nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50474660(CHEMBL111771)
Affinity DataKi:  22nMAssay Description:In vitro binding affinity towards alpha-1A adrenergic receptor of rat submaxillary gland in radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50474632(CHEMBL327116)
Affinity DataKi:  22nMAssay Description:In vitro binding affinity towards alpha-2B adrenergic receptor of rat neonatal lung in radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193306((E)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propa...)
Affinity DataKi:  22.8nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50474632(CHEMBL327116)
Affinity DataKi:  23nMAssay Description:In vitro binding affinity towards alpha-2A adrenergic receptor of human clone in radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193315((E)-1-(4-chlorophenyl)-3-(3',4',5',6'-tetrahydro-2...)
Affinity DataKi:  25.3nMAssay Description:Displacement of [3H]PIPAT from human recombinant D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193312((E)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propa...)
Affinity DataKi:  25.4nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145083(2-[4-(3-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataKi:  26.5nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193289((E)-1-(3,4-dimethylphenyl)-3-(4-pyridin-2-ylpipera...)
Affinity DataKi:  27.5nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50471340(CHEMBL317912)
Affinity DataKi:  31nMAssay Description:In vitro binding affinity towards alpha-1D adrenergic receptor of rat clone in radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193317((Z)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)pr...)
Affinity DataKi:  32.1nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145079(2-(4-Phenyl-piperazin-1-ylmethyl)-1H-benzoimidazol...)
Affinity DataKi:  33nMAssay Description:Binding affinity tested against D4.2 receptor in Chinese hamster ovary cell line (CHO cells) using [3H]spiperone as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50118703(CHEMBL109783 | N-[5-(4,5-Dihydro-1H-imidazol-2-yl)...)
Affinity DataKi:  33nMAssay Description:In vitro binding affinity towards alpha-2A adrenergic receptor of human clone in radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50474630(CHEMBL108804)
Affinity DataKi:  36nMAssay Description:In vitro binding affinity towards alpha-1A adrenergic receptor of rat submaxillary gland in radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193323((E)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propa...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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