Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Institute of Imaging Science
Curated by ChEMBL
Vanderbilt University Institute of Imaging Science
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of glutamate induced-calcium mobilization prei...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor allosteric binding site (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Institute of Imaging Science
Curated by ChEMBL
Vanderbilt University Institute of Imaging Science
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGlu5 expressed in HEK293A cells after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Displacement of [3H]-NMS from rat muscarinic M5 receptor stably expressed in CHO cells membrane by topCount scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair