Compile Data Set for Download or QSAR
maximum 50k data
Found 22 with Last Name = 'boldescu' and Initial = 'v'
TargetGenome polyprotein(Dengue virus)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50470562(CHEMBL1230055)
Affinity DataKi:  170nMAssay Description:Inhibition of N-terminal GST tagged recombinant Dengue virus 3 2'-O methyltransferase expressed in Escherichia coli BL21 cells by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataKi:  750nMAssay Description:Non-competitive inhibition of Dengue virus 4 NS3 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataKi:  750nMAssay Description:Non-competitive inhibition of Dengue virus 3 NS3 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50030464(CHEMBL3344310)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of Dengue virus 1 NS2B-NS3 protease expressed in Escherichia coli using Abz-RRRRSAG-nY-NH2 as substrate preincubated for 20 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50030464(CHEMBL3344310)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibition of Dengue virus 2 NS2B-NS3 protease expressed in Escherichia coli using Abz-RRRRSAG-nY-NH2 as substrate preincubated for 20 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50026808(CHEMBL2440341)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Dengue virus 2 NS2B-NS3 protease using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr as substrate preincubated for 15 mins followed by addition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50534351(CHEMBL4531266)
Affinity DataKi:  7.00E+3nMAssay Description:Mixed noncompetitive inhibition of the Dengue virus 2 NS2B-NS3 protease expressed in Escherichia coli using Boc-GRR-AMC as substrate assessed as enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50030464(CHEMBL3344310)
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of Dengue virus 4 NS2B-NS3 protease expressed in Escherichia coli using Abz-RRRRSAG-nY-NH2 as substrate preincubated for 20 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50513887(CHEMBL4458555)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of recombinant Dengue virus type 2 NS2B-NS3 protease expressed in Escherichia coli C41 cells using GRR-AMC as substrate after 15 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50534351(CHEMBL4531266)
Affinity DataKi:  1.50E+4nMAssay Description:Mixed noncompetitive inhibition of the Dengue virus 2 NS2B-NS3 protease expressed in Escherichia coli using Boc-GRR-AMC as substrate assessed as enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50026784(CHEMBL2440339)
Affinity DataKi:  1.56E+4nMAssay Description:Inhibition of Dengue virus 2 NS2B-NS3 protease using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr as substrate preincubated for 15 mins followed by addition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50030464(CHEMBL3344310)
Affinity DataKi:  2.44E+4nMAssay Description:Inhibition of Dengue virus 3 NS2B-NS3 protease expressed in Escherichia coli using Abz-RRRRSAG-nY-NH2 as substrate preincubated for 20 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50:  41nMAssay Description:Inhibition of Dengue virus ribose 2'-O methyltransferase using RNA substrate after 20 mins in presence of [methyl-3H]-AdoMet by microbeta counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  490nMAssay Description:Inhibition of Dengue virus ribose 2'-O methyltransferase using RNA substrate after 20 mins in presence of [methyl-3H]-AdoMet by microbeta counting an...More data for this Ligand-Target Pair
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50534349(CHEMBL4447800)
Affinity DataIC50:  500nMAssay Description:Inhibition of Dengue virus 2 NS3 helicase incubated for 2 mins followed by ATP additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50509461(CHEMBL4440832)
Affinity DataIC50:  990nMAssay Description:Inhibition of Dengue virus 3 NS2B-NS3 protease expressed in Escherichia coli BL21(DE3) using PhAc-Lys-Arg-Arg-AMC as substrate after 10 mins by fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50534349(CHEMBL4447800)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of RNA unwinding activity of thioredoxin/His6 tagged Dengue virus 2 TSV01 NS3 helicase (171 to 618 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50534350(CHEMBL4436496)
Affinity DataIC50:  2.75E+3nMAssay Description:Inhibition of the Dengue virus 2 NS2B-NS3 protease expressed in Escherichia coli BL21(DE3)-RIPL cells using Pyr-RTKR-AMC as substrate preincubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50509461(CHEMBL4440832)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Dengue virus 2 GFP/DsRed fused NS2B-NS3 protease co-transfected in HEK293T cells by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50509461(CHEMBL4440832)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of Dengue virus 2 NS2B-NS3 protease expressed in Escherichia coli BL21(DE3) using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50525242(CHEMBL4441561)
Affinity DataIC50:  5.95E+3nMAssay Description:Inhibition of recombinant Dengue virus 2 S-16803 NS2B-NS3 protease using Bz-nKRRAMC as substrate preincubated with enzyme followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50525243(CHEMBL4457482)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of Dengue virus 2 Taiwanese PL046 NS2B-NS3 protease using Ac-TTSTRR-pNA as substrate preincubated for 10 mins followed by addition of subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed