Affinity DataIC50: 0.0160nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Tested in vitro for inhibition against Prostaglandin G/H synthase 2 in human blood (95% confidence limits)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Tested in vitro for inhibition against Prostaglandin G/H synthase 2 in human blood (95% confidence limits)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Tested in vitro for inhibition against Prostaglandin G/H synthase 1 in human bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 1.67nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Tested for binding affinity against human NK-1 receptor transfected on CHO cells using [125I]-Tyr] SP as radioligandMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 9.30nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institut De Recherche Servier
Curated by ChEMBL
Institut De Recherche Servier
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair