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Found 224 with Last Name = 'broqua' and Initial = 'p'
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290967(1-{(5R,7S,8S)-8-[(2-Benzofuran-4-yl-acetyl)-methyl...)
Affinity DataKi:  0.100nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-U-69,593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50088375(1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...)
Affinity DataKi:  0.640nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-U-69,593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell lineMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290967(1-{(5R,7S,8S)-8-[(2-Benzofuran-4-yl-acetyl)-methyl...)
Affinity DataKi:  87nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-DAGO to rat brain mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50088375(1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-DAGO to rat brain mu opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102443(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Cbm)]-D-[Aph(...)
Affinity DataIC50:  2.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102449(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-Pal-L...)
Affinity DataIC50:  2.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102466(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-[Aph(...)
Affinity DataIC50:  3nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102451(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-Arg-D-Glu(Nal)-Leu...)
Affinity DataIC50:  3.30nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102442(ABARELIX | Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Nalpha...)
Affinity DataIC50:  3.5nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102454(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-Tyr-D-Har(Et2)-Leu...)
Affinity DataIC50:  3.60nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50369965(CETRORELIX | Cetrotide)
Affinity DataIC50:  4.20nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102435(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-[Aph(...)
Affinity DataIC50:  4.30nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102446(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(EtCbm)]-D-[Ap...)
Affinity DataIC50:  5nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102448(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-[Amf(...)
Affinity DataIC50:  5.5nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102441(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-[Amf(...)
Affinity DataIC50:  5.60nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102445(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-Cit-L...)
Affinity DataIC50:  5.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102434(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Ac)]-D-[Aph(C...)
Affinity DataIC50:  6.10nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102447(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Ac)]-D-[Amf(C...)
Affinity DataIC50:  6.40nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102456(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Ac)]-D-[Aph(A...)
Affinity DataIC50:  6.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50209591(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Atz)]-D-[Aph(...)
Affinity DataIC50:  6.90nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102459(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(DHor)]-D-[Amf...)
Affinity DataIC50:  7nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102462(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Cbm)]-D-[Aph(...)
Affinity DataIC50:  7.20nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102467(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-[Aph(...)
Affinity DataIC50:  7.70nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102465(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(DHor)]-D-[Amf...)
Affinity DataIC50:  7.70nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102438(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-[Amf(...)
Affinity DataIC50:  7.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102453(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-[Amf(...)
Affinity DataIC50:  7.90nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102433(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Amf(Hor)]-D-[Aph(...)
Affinity DataIC50:  7.90nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102458(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Nalpha-Me-Aph(Hor...)
Affinity DataIC50:  8.10nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102460(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(D/L-Hya)]-D-[...)
Affinity DataIC50:  8.10nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102464(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Dhp)]-D-[Aph(...)
Affinity DataIC50:  8.20nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102461(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(DHor)]-D-[Aph...)
Affinity DataIC50:  8.60nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102437(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-[Amf(...)
Affinity DataIC50:  8.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102450(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(DHor)]-D-[Aph...)
Affinity DataIC50:  8.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102457(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(diureidoacety...)
Affinity DataIC50:  8.90nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102432(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Imz)]-D-[Aph(...)
Affinity DataIC50:  9.10nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102444(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-[Amf(...)
Affinity DataIC50:  9.5nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102452(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Oro)]-D-[Aph(...)
Affinity DataIC50:  10.7nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102440(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(DImz)]-D-[Aph...)
Affinity DataIC50:  10.8nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102439(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-[Aph(...)
Affinity DataIC50:  10.8nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102436(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Hor)]-D-Nal-L...)
Affinity DataIC50:  13nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290968(9H-Fluorene-9-carboxylic acid methyl-((1S,2S)-2-py...)
Affinity DataEC50:  22nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290969(2-(4-Chloro-phenyl)-3-phenyl-cycloprop-2-enecarbox...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50088375(1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...)
Affinity DataEC50:  9.60nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290970(2,3-Diphenyl-cyclopropanecarboxylic acid methyl-((...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290971(2,3-Diphenyl-cycloprop-2-enecarboxylic acid methyl...)
Affinity DataEC50:  32nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290972(1-[Methyl-((1S,2S)-2-pyrrolidin-1-yl-cyclohexyl)-c...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290973(CHEMBL318430 | N-Methyl-3,3-diphenyl-N-((1S,2S)-2-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290967(1-{(5R,7S,8S)-8-[(2-Benzofuran-4-yl-acetyl)-methyl...)
Affinity DataEC50:  3.30nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290974(CHEMBL327944 | N-Methyl-2,2-diphenyl-N-((1S,2S)-2-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290975(2-(3-Methoxy-phenyl)-3-phenyl-cycloprop-2-enecarbo...)
Affinity DataEC50:  300nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
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