Affinity DataKi: 0.100nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-U-69,593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell lineMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-U-69,593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell lineMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-DAGO to rat brain mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-DAGO to rat brain mu opioid receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 10.7nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 10.8nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 10.8nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute
Curated by ChEMBL
Ferring Research Institute
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: 9.60nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: 3.30nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair