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Found 248 with Last Name = 'buchman' and Initial = 'cd'
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236899(CHEMBL4099822)
Affinity DataKi:  19nMAssay Description:Competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity using pro...More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236900(CHEMBL4072941)
Affinity DataKi:  35nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459608(CHEBI:90441 | CHEMBL3276621)
Affinity DataKi:  56nMAssay Description:Inhibition of human ALDH1A2More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236900(CHEMBL4072941)
Affinity DataKi:  87nMAssay Description:Competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity using pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236904(CHEMBL1335126)
Affinity DataKi:  170nMAssay Description:Uncompetitive inhibition of full length recombinant human ALDH1A1 expressed in Escherichia coli BL21(DE3) using propionaldehyde as substrate in prese...More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459608(CHEBI:90441 | CHEMBL3276621)
Affinity DataKi:  261nMAssay Description:Inhibition of human ALDH1A3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459608(CHEBI:90441 | CHEMBL3276621)
Affinity DataKi:  285nMAssay Description:Inhibition of human ALDH1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236901(CHEMBL4061563)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459601(CHEMBL4217738)
Affinity DataKi:  380nMAssay Description:Non-competitive inhibition of human recombinant ALDH1A1 assessed as reduction of NAD(P)H formation using varying levels of NAD+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50078833(4-Methyl-7-(diethylamino)coumarin | 7-(diethylamin...)
Affinity DataKi:  870nMAssay Description:Non-competitive inhibition of full length recombinant human ALDH1A1 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase ac...More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236904(CHEMBL1335126)
Affinity DataKi:  1.10E+3nMAssay Description:Competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity using pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50078833(4-Methyl-7-(diethylamino)coumarin | 7-(diethylamin...)
Affinity DataKi:  1.20E+3nMAssay Description:Non-competitive inhibition of full length recombinant human ALDH1A1 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase ac...More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236910(CHEMBL4083412)
Affinity DataKi:  2.40E+3nMAssay Description:Competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity using pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50303403(2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetonitrile ...)
Affinity DataKi:  5.60E+3nMAssay Description:Mixed-type non-competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50303403(2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetonitrile ...)
Affinity DataKi:  6.90E+3nMAssay Description:Non-competitive inhibition of full length recombinant human ALDH1A1 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase ac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567384(CHEMBL4849586)
Affinity DataIC50:  21nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567363(CHEMBL4876602)
Affinity DataIC50:  34nMAssay Description:Inhibition of human ALDH1A3 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567363(CHEMBL4876602)
Affinity DataIC50:  40nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567386(CHEMBL4861872)
Affinity DataIC50:  50nMAssay Description:Inhibition of human ALDH1A3 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50076742(CHEBI:86194 | CHEMBL3416563)
Affinity DataIC50:  57nMAssay Description:Inhibition of human ALDH1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567385(CHEMBL4846203)
Affinity DataIC50:  58nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567382(CHEMBL4859904)
Affinity DataIC50:  60nMAssay Description:Inhibition of human ALDH1A3 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567372(CHEMBL4875157)
Affinity DataIC50:  63nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236909(CHEMBL4090473)
Affinity DataIC50:  65nMAssay Description:Inhibition of full length recombinant human ALDH1A2 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567383(CHEMBL4847114)
Affinity DataIC50:  65nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236905(CHEMBL1349972)
Affinity DataIC50:  67nMAssay Description:Inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity by measuring NAD(P)H ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236909(CHEMBL4090473)
Affinity DataIC50:  67nMAssay Description:Agonist effect on the Dopamine D4.2 receptor was determined by evaluating effective concentration causing stimulation of mitogenesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567384(CHEMBL4849586)
Affinity DataIC50:  68nMAssay Description:Inhibition of human ALDH1A1 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236908(CHEMBL1562069)
Affinity DataIC50:  69nMAssay Description:Inhibition of full length recombinant human ALDH1A2 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567363(CHEMBL4876602)
Affinity DataIC50:  70nMAssay Description:Inhibition of human ALDH1A1 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567362(CHEMBL4848258)
Affinity DataIC50:  73nMAssay Description:Inhibition of human ALDH1A3 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567382(CHEMBL4859904)
Affinity DataIC50:  80nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459603(CHEMBL4213331)
Affinity DataIC50:  80nMAssay Description:Inhibition of human ALDH1A1 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459588(CHEMBL4210115)
Affinity DataIC50:  80nMAssay Description:Inhibition of human ALDH1A1 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459603(CHEMBL4213331)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant ALDH1A1 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459588(CHEMBL4210115)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant ALDH1A1 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldehyde dehydrogenase X, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236908(CHEMBL1562069)
Affinity DataIC50:  86nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567372(CHEMBL4875157)
Affinity DataIC50:  89nMAssay Description:Inhibition of human ALDH1A3 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567373(CHEMBL4855442)
Affinity DataIC50:  89nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459603(CHEMBL4213331)
Affinity DataIC50:  90nMAssay Description:Inhibition of human ALDH1A3 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459603(CHEMBL4213331)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant ALDH1A3 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567376(CHEMBL4848831)
Affinity DataIC50:  91nMAssay Description:Inhibition of human ALDH1A3 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567386(CHEMBL4861872)
Affinity DataIC50:  93nMAssay Description:Inhibition of human ALDH1A1 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567374(CHEMBL4849624)
Affinity DataIC50:  94nMAssay Description:Inhibition of human ALDH1A1 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567373(CHEMBL4855442)
Affinity DataIC50:  95nMAssay Description:Inhibition of human ALDH1A3 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase X, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236909(CHEMBL4090473)
Affinity DataIC50:  95nMAssay Description:Inhibition of full length recombinant human ALDH1B1 expressed in Escherichia coli TunerDE3 assessed as reduction in dehydrogenase activity by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567374(CHEMBL4849624)
Affinity DataIC50:  100nMAssay Description:Inhibition of human ALDH1A3 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50459609(CHEMBL4214000)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant ALDH1A1 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567382(CHEMBL4859904)
Affinity DataIC50:  100nMAssay Description:Inhibition of human ALDH1A1 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567376(CHEMBL4848831)
Affinity DataIC50:  100nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
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