TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School
Massachusetts General Hospital and Harvard Medical School
Affinity DataIC50: 0.5nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 13nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of BMP2-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of ALK1 (unknown origin) expressed in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of ALK2 (unknown origin) expressed in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 27nMAssay Description:Inhibition of BMP4-induced BMP receptor in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 37nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 38nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 39nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 40nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School
Massachusetts General Hospital and Harvard Medical School
Affinity DataIC50: 43nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School
Massachusetts General Hospital and Harvard Medical School
Affinity DataIC50: 47.6nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 60nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 100nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of TGFbeta1-induced TGFbeta type 1 ALK5 in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School
Massachusetts General Hospital and Harvard Medical School
Affinity DataIC50: 105nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of TGFbeta1-induced TGFbeta type 1 ALK5 in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 130nMAssay Description:Inhibition of Escherichia coli TrmDMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 140nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair